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Yıl:2008; Cilt: 46; Sayı: 2>> Özet
TAM METİN
Yeni Symposium; 2008;46(2):70-73
Son Dönem Böbrek Yetmezliği Hastalarında Majör Depresif Bozukluğun Değerlendirilmesi
AE Yazıcı, P Erdem, K Yazıcı, ŞT Acar, AD Başterzi, A Erdem
Mersin Üniversitesi Psikiyatri AD, Mersin
Amaç: Son dönem böbrek hastalığına bağlı yetmezlik (SDBY) insidansı hızla artmaktadır. Bu ne¬denle SDBY olan hastaların prognozlarını etkileyen faktörlerle ilgili çalışmalar hız kazanmıştır. Son yıllarda psikososyal sorunlarla hastaların uzun dönem sonuçları arasındaki ilişkiler açığa çıktıkça bu konu üzerine daha fazla odaklanılmıştır Bu çalışmada diyalize giren bir grup SDBY hastasında ma¬jör depresif bozukluk (MDB) yaygınlığının değerlendirilmesi amaçlanmıştır.
Yöntem: Mersin'deki özel bir hemodiyaliz ünitesinde düzenli hemodiyaliz tedavisi görmekte olan hastalar Zung Ölçeği uygulanarak depresyon açısından tarandı. Zung Ölçeği ile SDS ölçümü %50 ve üstünde olan hastalar ile psikiyatrik görüşme yapılarak tanıları değerlendirildi. Bulgular: Çalışmaya katılmayı kabul eden ve Zung Ölçeği uygulanan 145 hastanın hiçbirisinin geç¬mişte veya son dönemde psikiyatrik başvurusu yoktu. Bu hastaların 70'inde SDS ölçümü %50'nin üzerindeydi. Bu 70 hastaya yapılan psikiyatrik muayene sonucunda 67 (%46) hastaya DSM IV TR kriterlerine göre MDB tanısı kondu.
Tartışma: Diyaliz hastalarında depresyon prevalansı çeşitli çalışmalarda %0-100 arasında değiş¬mekle birlikte genellikle %30-50 arasındadır. Bu çalışmada MDB tanısı birebir yapılan psikiyatrik muayene sonucunda DSM IV TR'ye göre konmuştur ve SDBY hastalarında MDB oranı %46 bulun¬muştur. SDBY nedeniyle diyalize giren hastalarda MDB sık görülmektedir. Ancak çalışmamız, psiki¬yatrik komorbiditenin göz ardı edildiğini düşündürmektedir.
Sonuç: SDBY'nin seyri ve sonlanışını etkileme potansiyeli olan depresyonun tanınması ve tedavisi önemlidir. Bu nedenle hastaların ve psikiyatri dışı sağlık çalışanlarının SDBY hastalarındaki MDB ris¬ki hakkında bilgilendirilmesi gerekmektedir.
Evaluation of Major Depressive Disorder in End Stage Renal Disease Patients
Objective: The incidence of end stage renal disease (ESRD) is increasing rapidly. Therefore, studies about factors influencing the prognosis of these patients are gaining speed. As the association between the psychosocial problems and the long term results revealed in many recent studies, focusing on this issue has increased. This study aimed to evaluate the prevalence of major depressive disorder (MDD) in a group of ESRD patients undergoing hemodialysis.
Method: Patients with ESRD undergoing hemodialysis in a private hemodialysis unit in Mersin (Turkey) were screened for depression using Zung Scale. Patients with SDS scores above 50% in Zung Scale were interviewed to evaluate diagnosis.
Results: 145 patients agreed to participate in the study and filled in the Zung Scale. Seventy pa¬tients had SDS scores above 50%. After psychiatric interview with these 70 patients, 67 were diagnosed MDD according to DSM-IV-TR criteria. None of the 145 participants, including patients diagnosed MDD had a history of past or recent referral to psychiatry.
Discussion: Although the reported rates of prevalence of depression in patients with ESRD vary between 0-100% in different studies, it is generally thought to be 30-50%. With a person-to-person interview, we found that 46% of patients met diagnostic criteria for MDD. MDD is seen frequently in patients with ESRD. However, our data suggest that psychiatric comorbidity is ignored in this group of patients.
Conclusion: It is important to diagnose and treat MDD which may potentially influence the course and prognosis of ESRD. Thus, information concerning MDD risk in ESRD should be provided for patients and non-psychiatric healthcare professionals.

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