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Yıl:2007; Cilt: 10; Sayı: 2>> Özet
TAM METİN
Klinik Psikiyatri Dergisi; 2007;10(2):63-68
Bipolar Bozukluk Başlangıç Yaşının Klinik ve Gidiş Özellikleriyle İlişkisi
R Tütüncü, S Örsel, MH Özbay
Dışkapı Eğitim ve Araştırma Hastanesi Psikiyatri Kliniği, Ankara
Amaç: Bu çalışmada bipolar bozukluk tanısı alan hastaların
başlangıç yaşlarının; sosyo-demografik değişkenlere,
klinik özelliklere, gidiş belirleyicilerine ve işlevselliğe
etkisinin araştırılması amaçlanmıştır. Yöntem: Çalışmaya,
başlangıç yaşı 20 yaş üstünde 23 hasta, 20 yaş ve altında
olan 20 hasta olmak üzere toplam 43 hasta alınmıştır.
Hastalık tanıları, DSM-IV Eksen I Bozuklukları için
Yapılandırılmış Klinik Görüşme (SCID-I) kullanılarak belirlenmiştir.
Tüm hastalar sosyo-demografik Bilgi Formu,
Young Mani Derecelendirme Ölçeği (YMRS), Hamilton
Depresyon Ölçeği (HAM-D), Global Değerlendirme Ölçeği
(GAS) ile değerlendirilmiştir. Bulgular: Erken başlangıçlı
hastalarda geç başlangıçlı hastalara göre çalışmama
oranları daha fazla, çocuk sahibi olma oranları belirgin
olarak daha az saptanmıştır. GAS skorlarına göre erken
ve geç başlangıçlı bipolar bozukluğu olan hastalarda orta
halli semptomlar veya genel olarak bazı zorluklarla
yürütülen işlevsellik söz konusudur. Her iki grup arasında
hastalığın gidişiyle ilgili anlamlı farklılıklar saptanmamıştır.
Ortalama hastalık süresinin her iki grupta da
benzer olması (GRUP 1: 12,95 yıl; GRUP 2 12,09 yıl) ve
GRUP 1 yaş ortalamasının 28.80 ve GRUP 2 ortalamasının
42,22 olması önemlidir. Sonuç: Bipolar bozuklukta,
başlangıç yaşından çok hastalığın süresinin gidişte etkili
olduğu düşünülmüş, erken başlangıç yaşının tek başına
bir alt tip göstergesi olmadığı görüşü desteklenmiştir.
Relationship Between Age of Onset in Bipolar Disorder and Clinical, Prognostic Properties
Objectives: The aim of this study is to investigate the
effect of age of onset on socio-demographic variables,
clinical properties, prognosis and functionality in bipolar
disorder. Method: The study sample consisted of 43
patients. 23 patients' age of onset was more than 20
and the rest was equal to or less than 20 [year]s old. The
patients' diagnosis was made by the help of the
Structured Clinical Interview for DSM-IV-TR (SCID-I). All
patients were assessed by socio-demographic form,
Young Mania Rating Scale (YMRS), Hamilton Depression
Rating Scale (HAM-D), and Global Assessment Scale
(GAS). Results: Unemployment rate was detected significantly
higher and children number lower in early
onset patients. According to GAS scores there were
moderate symptoms and some difficulties in functioning.
No significant differences were found in terms of
course of the disease. It is important to express that
average duration of the illness is same in both groups
(GROUP 1: 12,95 [year]s; GROUP 2 12,09 [year]s) and the
average age of the groups are 28,80 [year]s for GROUP 1,
and 42,22 [year]s for GROUP 2. Conclusion: Duration of
the illness is more important than the age of onset in
course of the bipolar disorder. Early age of onset might
not be the subtype predictor alone.

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