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Yıl:1996; Cilt: 34; Sayı: 1-2>> Özet
TAM METİN
Yeni Symposium; 1996;34(1-2):15-18
Elektrokonvulsiv Tedavi ile Hafıza Kusuru Ortaya Çıkma Olasılığının Önceden Tahmini
K Arıkan, Ö Oran, A Kalyoncu, Z Kökrek
İ.Ü. Cerrahpaşa Tıp Fak. Psikiyatri ABD, İstanbul
ilk ECT sonrasında plasma çinko seviyesinde ortaya çıkan dalgalanmaları takip ettik. Bu dalgalanmaların
büyüklüğü ile ECT'ye bağlı hafıza kusurları arasında bir ilişki olup olmadığını inceledik. Birinci ECT'den 15
ve 30 dakika sonra plazma çinko seviyesi yükselen olgularda beşinci ECT'den 24 saat sonra test edilen
hafıza performanslarında bozukluk olduğunu gördük. ECT'ye bağlı hafıza kusuru gözlenen populasyondaki
spesifik plazma çinko profili hafıza kusuruna yol açan patoloji ile doğrudan bağlantılı olabileceği gibi.
beyin veya kan beyin bariyerindeki homeostasisin elektrisite nedeniyle bozukluğunu yansıyor olabileceği
yorumuna ulaştık.
Predicition of the Memory Related Side Effect of The Electroconvulsive Therapy (ECT)
We have monitored the fluctuations in plasma zinc concentrations after the first ECT. Then we investigated
if the magnitude of these changes have a predictive value for the ECT induced impairment in memory.
Subjects who showed the increase of plasma zinc concentration between 15 and 30 minutes after the first
ECT were at risk for memory impairment 24 hrs after the fifth ECT. The specific profile of the changes in
plasma zinc concentration appeared in the memory impaired population may be related to the underlying
pathology directly or it is an indirect phenomenon for the brain and/or blood brain barrier homeostasis disturbed
byelectricity.

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