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Yıl:2007; Cilt: 18; Sayı: 2>> Özet
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Türk Psikiyatri Dergisi; 2007;18(2):118-128
Hafif Kognitif Bozukluğu Olan Hastalarla Alzheimer Tipi Demans Hastalarının Örtük Bellek Performansı Açısından Karşılaştırılması
A Akdemir, B Cangöz, S Örsel, K Selekler
Mustafa Kemal Ü. Tıp Fak. Psikiyatri ABD, Hatay
Amaç: Örtük bellek, bilginin bilinçsiz, otomatik ve farkında olmaksızın hatırlanması olarak tanımlanmaktadır ve bu açıdan açık bellekten farklıdır. Bu çalışmada, hafif bilişsel bozukluğu olan hastalar, ATD hastaları (farklı evrelerdeki) ve sağlıklı kontrol grubu örtük bellek performansı açısından karşılaştırılmıştır.

Yöntem: Çalışmaya HBB tanısı olan 19, ATD tanısı olan 23 hasta alınmıştır. ATD’lı hastalardan 11’i hafif-orta, 12’si ağır evrededir. Kontrol grubu yaş, cinsiyet, eğitim düzeyi ve el tercihi açısından hasta gruplarıyla eşleştirilmiştir. Klinik değerlendirme için DSM-IV ve NINCDS-ADRA tanı ölçütleri kullanılmıştır.

Bulgular: 4x3 faktörlü ANOVA sonucunda, bilgi işleme düzeyi değişkeninin temel etkisi ile grup ve bilgi işleme düzeyi değişkenlerinin ortak etkisi anlamlı bulunmuştur. Grup değişkeninin temel etkisi anlamlı değildir.

Sonuç: HBB ve ATD hasta grupları örtük bellek görevinde benzer performans göstermişlerdir. HBB ve ATD hasta gruplarında örtük bellek performansı korunmuştur. Buna karşın, hasta gruplarının, örtük bellek performansı bilgi işleme düzeyi manipülasyonuna göre değişebilmektedir. Sonuç olarak, ATD’ın klinik değerlendirmesinde örtük bellek görevlerinin kullanılması önemlidir.
A Comparison of Implicit Memory Performance in Mild Cognitive Impairment and Alzheimer Type Dementia Patients
Objective: Implicit memory, defined as the recollection of knowledge unconsciously, automatically, and without being aware of it, is different than explicit memory, in which knowledge is recollected consciously, while being aware of it. In the present study, the implicit memory performance of patients with mild cognitive impairment (MCI) and Alzheimer’s type dementia (ATD) (different stages) were compared to healthy controls.

Method: The study included 19 MCI patients and 23 ATD patients (11 mild-moderate and 12 severe stage ATD). Control subjects were matched to the patient groups according to age, gender, education, and hand preference. DSM-IV and NINCDS-ADRA diagnostic criteria were used for clinical assessment.

Results: The 4 × 3 ANOVA revealed a significant main effect of the level of processing, and group and level of processing interaction effect was also significant. Group main effect was not significant.

Conclusion: MCI and ATD groups performed similarly on the implicit memory task. Implicit memory performance was intact in patients with MCI and ATD; however, implicit memory performance of the patient groups differed according to the level of processing manipulation. For that reason, implicit memory tasks should be used for clinical diagnosis in ATD.

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