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Yıl:2007; Cilt: 44; Sayı: 1>> Özet
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Nöropsikiyatri Arşivi; 2007;44(1):19-27
Dikkat Eksikliği/Hiperaktivite Bozukluğu Olan Çocuklarda Kantitatif EEG Analizi
A Özge, F Toros, Ü Çömelekoğlu, H Kaleağası
Mersin University School of Medicine, Turkiye
Çocuk ve ergenlerde dikkat eksikliği hiperaktivite bozukluğu (DEHB) aşırı huzur­suzluk ve dikkat aralığının çok dar olması ile karakterize olup dürtüsel ve yıkıcı davranışlara yol açan bir tablodur. DEHB olan çocuklarda posterior bölgelerde hakim olmak üzere yavaş dalga aktivitesinde artış ve beta aktivitesinde azalma sıklıkla bildirilmiştir. Bu kesitsel çalışmayı DEHB tanısı alan çocuklar ve kontrol­lerde kantitatif EEG analizi kullanarak ortaya çıkan değişiklikleri saptamak ve gerek hemisferik, gerekse bölgesel farklılıkları karşılaştırmak amacı ile gerçek­leştirdik. Biz DSM-IV'e gore DEHB tanısı alan 24 çocuk ve 21 yaş -cins uyumlu kontrolü değerlendirdik. Aynı uzman tarafından istirahat durumunda ve hiper-ventilasyonda klinik değerlendirme ve EEG analizi yapıldı. EEG kayıtlarının gör­sel olarak değerlendirilmesinde herhangi bir anormallik sapatnmadı ancak KE-EG analizinde istirahat durumunda teta aktivitesinde azalma, hiperventilasyon-da ise beta ve alfa aktivitelerinde artışa eşlik eden delta aktivitesinde azalma kaydedildi. DEHB tanısı alan çocuklarda hemsiferik asimetri, sol frontotemporal bölgede hakim olmak üzere dalga frekansları ile (delta ve teta) erkek cinsiyeti ve yaş arasında anlamlı ilişki saptandı.
KEEG analizinin DEHB'nun klinik değerlendirmesinde objektif ve fizyolojik te­melli veri sağlayan yararlı bir yöntem olarak kullanılabileceği ve hastalığın nörobiyolojik temeline katkısı olacağı sonucuna varıldı.
Quantitative EEG Analysis in Children with Attention Deficity/Hyperactivity Disorders
Attention deficit hyperactivity disorder (AD/HD) in children and adolescents is characterized by excessive restlessness and extremely poor concentration span, resulting in impulsive and disruptive behaviour. Increased slow wave ac­tivity and decreased beta activity, predominantly in posterior regions, have be­en reported in AD/HD. We performed this cross-sectional study to determine and compare hemispheric and regional differences in children with AD/HD and age-sex matched children by using the quantitative EEG (QEEG) analysis. We evaluated 24 children with AD/HD who were diagnosed by DSM-IV criteria and 21 age-sex matched controls. The clinical evaluation and EEG analysis, during the baseline and hyperventilation, had been performed by the same specialist. Visual analysis of EEG records did not show any important abnormality, but QE-EG analysis performed decreased theta activity during basic state, decreased delta, increased alpha and beta activities during hyperventilation. Hemispheric asymmetry, a relationship between wave frequencies (delta and theta), and male gender and age, especially in left frontotemporal regions, have been se­en in children with AD/HD.
As for conclusion, QEEG analysis can be accepted as a beneficial technique providing objective and physiologically based data currently available for clini­cal assessment, and some features can be added to the neurobiological basis of AD/HD.

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