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Yıl:2007; Cilt: 17; Sayı: 1>> Özet
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Klinik Psikofarmakoloji Bülteni; 2007;17(1):15-23
Ayaktan takip edilen şizofreni hastalarının takip sürelerini etkileyen sosyodemografik, hastalık ve tedaviye ait özellikler
A Sarandöl, C Akkaya, Ş Cangür, Ş Mercan, E Pirinççi, S Kırlı
Uludağ Üniversitesi Tıp Fakültesi, Psikiyatri AD, Bursa
Amaç: Ayaktan tedavi uygulamalarında uzun süre takipte kalan şizofreni hastalarının kısa süre takipte kalanlarla, sosyodemografik ve hastalı k özellikleri ile tedavi ve tedavi seyri açısından karşılaştırılması amaçlanmıştır.

Yöntem: Bu çalışma ile, hastaların Uludağ Üniversitesi Tıp Fakültesi Psikiyatri polikliniğine 01 Ocak 1998-31 Aralık 2005 tarihleri arasındaki ilk başvurularına ait dosya bilgileri retrospektif olarak incelendi. Hazırlanan özel bir form ile; hastaların sosyodemografik ve hastalık özellikleri, tedavi ve tedavi seyri araştırıldı. Çalışmaya dahil edilmiş olan 274 hasta; uzun süre (>2 yıl) ve kısa süre (<2 yıl) poliklinik takibinde kalanlar olarak iki grup halinde incelemeye alındı. İlk başlanan antipsikotik ilaçlar: atipik ve tipik antipsikotikler olarak iki gruba ayrıldı. Çalışma ile ilgili olarak etik kurul onayı alındı.

Bulgular: Uzun süre takipte kalan 131 hastanın 64’ünde (%48.9) takip süresince en az bir kez ilaç tedavisi değişikliğine gidilirken, kısa süre takipte kalan 143 hastanın ancak 24’ünde (%16.8) en az bir kez ilaç tedavisi değişikliği yapılmıştır (p<0.001). Uzun süre takipte kalanların %58’inde ilk başvurudaki antipsikotik değiştirilmemiş veya ek psikiyatrik ilaç kullanılmıştır. Uzun süre takipte kalanların kısa süre takipte kalanlara göre yaşı (p<0.01), antipsikotik kullanma süreleri (p<0.001), hastaneye yatış (p<0.001) ve atak sayıları (p<0.05) anlamlı derecede daha yüksekti. Uzun süre takipte kalanların antikolinerjik ajan (p<0.05) ve ek antipsikotik (p<0.01) kullanma oranları, kısa süre takipte kalanlardan anlamlı olarak daha fazlaydı.

Sonuç: Bu çalışmada, hastanın yaşının, antipsikotik kullanma süresinin, atak ve hastaneye yatış sıklığının şizofreni hastalarının poliklinik takip sürelerine etkisinin olabileceği dikkati çekmiştir
Sociodemographic, disorder and treatment relatedcharacteristics affecting follow-up periods of schizophrenic outpatients
Objective: This study aims to compare the long term monitoredschizophrenic patients to short term monitored patients with respectto sociodemographic, disorder and treatment characteristics andprognosis in outpatient practices. Method: In this study, files of schizophrenic patients referred first timeto the outpatient psychiatry clinic of Medical School of UludagUniversity during the [year]s 1998-2005 were examined. With a form,socio-demographic, disorder and treatment characteristics andprognosis of the patients were questioned. The recruited 274 patientswere examined in two groups as long term monitored (>2 [year]s)patients and short term monitored (<2 [year]s) patients. Initiallyprescribed antipsychotics were divided into two groups as Atypicaland Typical antipsychotics. Results: Sixty four of 131 long term monitored patients (48.9%)underwent treatment alteration at least once during the entire followup period while only 24 of 143 short term monitored patients (16.8%)underwent treatment modification at least once (p<0.001).Antipsychotic was not changed however some of them receivedanother psychotrophic agent in combination with the former one in58% of the patients that was followed up for long term. Age of thepatient (p<0.01), duration of antipsychotic use (p<0.001), frequency ofattacks (p<0.05), and hospitalization (p<0.001) were greater in longterm monitored patients. The use of anticholinerjic agents (p<0.05)and adjuvant antipsychotics (p<0.01) were much more common inlong term monitored patients.Conclusions: Age of the patient, duration of antipsychotic usage andfrequency of attacks and and hospitalization may influence themonitoring of the schizophrenic patients in the outpatient clinics

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