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Yıl:2006; Cilt: 13; Sayı: 3>> Özet
TAM METİN
Çocuk ve Gençlik Ruh Sağlığı Dergisi; 2006;13(3):117-123
Yaygın Gelişimsel Bozukluk Tanısı Olan Çocuklarda İlaç Kullanım Örüntüsü
HT Ulay, SEÇ Kültür
Hacettepe Üniv. Tıp Fak., Çocuk Ruh Sağlığı ve Hastalıkları Anabilim Dalı, Ankara
Amaç: Yaygın gelişimsel bozuklukların (YGB) etiyolojisine özgü ilaç tedavisi bilinmemektedir. Bununla birlikte YGB'lerde sosyal çekilme, aşırı hareketlilik, zarar verici davranışlar, yineleyici davranışlar gibi yakınmaların eşlik ettiği durumlarda ve YGB belirtilerinin tedavisinde %25-50 oranında ilaç tedavisi uygulandığı bilinmektedir. Bu çalışmada, bir çocuk ve ergen psikiyatrisi kliniğinde YGB tanısı konan çocuklarda ilaç kullanım örüntüsünün incelenmesi amaçlanmıştır. Yöntem: 2004-2005 yıllarında Hacettepe Üniversitesi Tıp Fakültesi Çocuk Ruh Sağlığı Anabilim Dalında YGB tanısı konarak değerlendirilen çocukların (s=97) dosyaları ilaç kullanım bilgileri açısından geriye dönük olarak incelenmiştir. Sonuçlar: YGB olan çocukların %41,2'sine (s=40) ilaç tedavisi önerildiği belirlenmiştir. İlaç kullanan çocuklarda en sık eşlik eden psikiyatrik belirtinin 9628,9 (s=28) oranıyla aşırı hareketlilik olduğu görülmüştür. YGB olan çocuklarda kullanılan psikotrop ilaçlar arasında en sık (s=33; %34,0) atipik antipsikotiklerin olduğu belirlenmiştir. İlaç kullanan çocukların yaş ortalamasının ilaç kullanmayanlara göre istatistiksel olarak anlamlı düzeyde daha yüksek olduğu saptanmıştır (t= 2,573, sd= 71.33; p < 0.05). Tartışma: Bu çalışmada yazından belirtilen uygulamalardan farklı olarak, YGB olan çocuklarda eşlik eden psikiyatrik belirtilerin tedavisinde antidepresan gruptan ilaçların kullanımının yaygın olmadığı görülmüştür. Bu dununun çalışma grubuna YGB tanılı yetişkin hastaların dahil olmaması ile ilişkili olabileceği düşünülmüştür. Gelecekte YGB'lere eşlik eden psikiyatrik belirtiler ve tedavi seçeneklerine yönelik çalışmalar yapılmasına ihtiyaç vardır.
Medication Patterns In Children With Pervasive Developmental Disorders
Objective: Although there is no specific treatment for the core features of pervasive developmental disorders (PDD). some of the behavioral symptoms may be treated pharmacologically. Pharmacotherapy is used in the treatment of 25-50% PDD children with symptoms such as social withdrawal, hyperactivity, aggression, and stereotypies. The aim of this study is to determine the profiles of psychotropic medication use in children with PDDs. Method: Children with PDD who were referred to Hacettepe University Department of Child and. Adolescent Psychiatry Clinic between 2004-2005 (n=97) were reviewed retrospectively. Results: Psychotropic medication was used in 41. 2% (n=40) of the children. Hyperactivity was the most common (28.9%. n=28) complains accompanying PDD symptoms who were taking psychotropic medication. Atypical antipsychotics (34,0%, n=33) were the most preferred drugs. Patients taking psychotropic medication were older than the children who were not taking psychotropic medication (t= 2.573. d/ = 71,33: p < 0.05). Discussion: Different from the literature, antidepressants were found not to be frequently preferred in the treatment of PDDs. This may be a result of the study group did not included adults with PDD. The results of this study highlight the need for more research on specific psychotropic medication for specific symptoms in children with PDDs.

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