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Yıl:2006; Cilt: 9; Sayı: 2>> Özet
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Klinik Psikiyatri Dergisi; 2006;9(2):75-81
Limbik Dizgenin Bir Üyesi Olarak Temporal Lob ve Psikiyatrideki Önemi: Davranışsal Sendromlar
İ Yaluğ, E Özten, Ö Bilge, AE Tufan
Kocaeli Ü. Tıp Fak. Psikiyatri ABD
Limbik sistem, psikiyatri ve nörolojinin kesiştiği bir alandır. Fokal temporolimbik yapılarda lezyonu olan hastalarda yapılan çalışmalar; duygudurum, kişilik özellikleri, davranış ve sosyal işlevsellikte semptom oluşabileceğini göstermektedir. Temporolimbik yapılarda meydana gelen bir hasarlanma hem nörolojik hem de psikiyatrik bulgulara yol açabilmektedir. Temporal lob epilepsisi, temporal bölge ile ilişkili inme, travma ve tümörler, klinikte karşımıza anksiyete ve duygudurum semptomları ile çıkabilir. Bu durum tanı karmaşasına yol açabilir. Bu nedenle temporal lobu tutan nörolojik hastalıklar psikopatolojinin ayırıcı tanısında göz önünde bulundurulmalıdır. Bu yazıda, temporal bölgeyi etkileyen hastalıklarda, özellikle de temporal lob epilepsisi, temporal bölge ile ilişkili tümör, travma ve inmelerde görülen psikiyatrik bulgular literatür taranarak ele alınmıştır. Yapılan birçok çalışmada, davranış bozukluklarının, duygudurum ve anksiyete bozukluklarının, temporolimbik yapı ile ilişkilendirilmesine karşın, hipokampus, amigdala ve çeşitli kortikal ve subkortikal alanları da içeren geniş ağın, duygulanım ve duygu kökenli davranışın oluşumunda etkili olduğu görülmektedir. Bazı hastalıklar spesifik olarak temporal lob lezyonlarıyla ilgili görünse de, birçok semptomu sadece temporal lobla veya bu lobun sağ veya sol tarafıyla ilişkilendirmek için çok kesin kanıtlar bulunmamaktadır. Duygu durumun ve davranış değişikliklerinin nörolojik bileşenlerini netleştirmek için daha geniş araştırmalara gereksinim duyulmaktadır.



Temporal Lobe as a Member of Limbic Circuit and Its Psychiatric Importance: Behavioral Syndromes
Limbic system is a subject that both psychiatry and neurology deal with. Studies have shown that patients present with changes in mood, personality, social functioning and behavior in focal temperolimbic lesions. It is thought that a lesion in temporolimbic region can both psychiatric and neurologic symptoms. Temporal lobe epilepsy, stroke, trauma and tumors in temporal lobe may present with anxiety and affective symptoms. Therefore neurological disorders involving the temporal lobe should be considered differential diagnosis is important for psychiatric disorders. This article reviews temporal lobe disorders, especially temporal lobe epilepsy, stroke, trauma and tumors presenting with psychiatric symptoms. Studies indicate that hippocampus, amygdala, cortical and subcortical areas mainly act in the formation of affect and behavior while temporolimbic areas are related to mood, anxiety and behavioral disorders. Although many disorders are connected to temporal lobe lesions, most of the symptoms may not be explained solely by damage to temporal lobe or its laterality. More studies are needed to demonstrate the neurobiological network involved in changes of mood and behavior.

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