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Yıl:1993; Cilt: 30; Sayı: 3>> Özet
Nöropsikiyatri Arşivi; 1993;30(3):398-403
Paroksizmal semptomlarla prezante olan iki multipl skleroz olgusu ve MRG bulguları
BB Kurt, O Ciğeroğlu, Z Kural, M Eraksoy
İstanbul Üniversitesi İstanbul Tıp Fakültesi Nöroloji Anabilim Dalı
Paroksizmal semptomlar iki dakikadan fazla sürmeyen, aynı hasta için stereotipik bir paterni sık olarak, kimi zaman günde yüzlerce kez tekrarlayan duysal veya motor fenomenlerdir. Multipl Sklerozda (MS) tanımlanmış olan çok sayıdaki paroksizmal semptomlardan en sık ve en önemli olanları tonik nöbetler ve paroksizmal dizartri-ataksidir. Bu semptomlar MS'in ilk belirtisi olarak ortaya çıktıklarında tanı güçlüklerine yol açabilmektedirler, bu nedenle akla gelmeleri önem taşımaktadır. Paroksizmal semptomların Manyetik Rezonans Görüntüleme (MRG) bulguları ile ilgili çok az sayıda bildiri bulunmaktadır. Biri tonik nöbetlerle prezante olan, diğeri de paroksizmal dizartri-ataksi ile kliniğimize başvuran iki MS olgusu ve MRG bulguları bildirilmiştir. Amacımız paroksizmal semptomlalrla MRG kolerasyonunu ve bu semptomlardan sorumlu olan mekanizmaları ilgili literatür ışığında tartışmaktır.
Two cases of multiple sclerosis with paroxysmal symptoms and their MRI findings
Paroxysmal Symptoms are brief, sensory or motor phenomena, lasting no more than two minutes and almost stereotyped for the individual patients, occuring very frequently, sometimes up to several hundred times in a day. An increasing variety of paroxysmal symptoms has been recognised in multiple sclerosis, the most important and frequent types among which are tonic seizures and dysarthria-ataxia. These symptoms presenting as initial features of MS can cause some diagnostic difficulties, therefore it is important to keep them in mind. There are only a few reports about the MRI findigns of paroxysmal symptoms. We report two cases of MS, one with tonic seizures and the other with paroxysmal dysarthria-ataxia and their MRI findings. Our aim is to discuss the correlation between paroxysmal symptoms and the MRI and to speculate the possible mechanisms, which are responsible for the occurence of there symptoms in the light of the literature.

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