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Yıl:1994; Cilt: 31; Sayı: 3>> Özet
Nöropsikiyatri Arşivi; 1994;31(3):142-145
Elektrokonvulsif Tedavinin Serum Total Kreatin Fosfokinaz ve Kardiyak İzoenzimler Üzerindeki Etkisi
S Görpeüoğlu, ME Önder
Numune Hastanesi Psikiyatri Kliniği, Ankara
Bu çalışma, şizofreni tanısı alan hastalarda elektrokonvulsif tedavi (EKT) öncesi ve sonrası serum total CPK, CPK-MB, LDH, SGOT, SGPT düzeylerini araştırarak, psikotik hastalarda arttığı bildirilen enzimleri EKT'nin ne yönde etkilediğini ortaya koymayı amaçlamaktadır. Serum total CPK ve kardiyak izoenzimlerin EKTden yanm saat önce ve EKTden 24 saat sonra düzeyleri ölçülmüştür. Bunlar arasındaki farklılık parametrik testlerde iki eş arasındaki farkın önemlilik testi ile araşürılmıştır. Araştırma EKT'nin şizofrenik hastalarda serum total CPK ve LDH düzeylerini arttırdığı, buna karşın CPK-MB, SGOT, SGPT düzeylerinde bir değişiklik oluşturmadığını göstermiştir.
The Effects of Electroconvulsive Therapy On Serum Total CPK and Cardiac Isoenzymes
This study aims to find out the effects of ECT on serum total CPK, CPK-MB, LDH, ALT and AST levels in schizophrenic patients by studying their enzyme levels before and after the therapy. Serum total CPK and cardiac isoenzyme levels were measured half an hour before and 24 hours after the ECT. The differences were evaluated by a parametric test namely, the statistically significance of the difference between two pairs. The study showed that ECT in schizophrenic patients elevates serum total CPK and LDH levels but does not change CPK-MB, ALT, AST levels.

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