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Yıl:2023; Cilt: 60; Sayı: 2>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2023;60(2):143-150
Pulmoner Emboli ve Uyku Apne İlişkisi
Ö Kahya, S N Sökücü, C Özdemir, S T Onur, M Sarı, Ş Aydın
Nevşehir Üniversitesi, Nevşehir
Amaç: Literatürde Obstruktif Uyku Apne Sendromu (OUAS) ile Pulmoner Tromboemboli (PTE) arasında bir ilişki olduğu, OUAS’ın PTE için bir risk faktörü olduğu çalışmalar mevcuttur. Çalışmamızda PTE hastalarında OUAS’ın prevalansını, PTE şiddeti ile ilişkisini ve bir aylık mortaliteye etkisini değerlendirmeyi amaçladık. Yöntem: Tek merkezli, prospektif, karşılaştırmalı vaka kontrol yönteminde olan çalışmamıza 01/07/2018–04/01/2020 arasında hastanemizde yatan, nonmasif PTE tanısı görüntüleme tanı yöntemleriyle ile kesinleştirilmiş 198 hasta alındı. Hastaların gündüz aşırı uyku hali Epworth anketiyle; OUAS riski Berlin, STOP, STOP-BANG uyku anketleri ile değerlendirildi. Hastaların demografik ve klinik verileri, komorbiditeleri, Pulmoner emboli şiddet indeksi (PESİ), basitleştirilmiş PESİ (SPESİ), WELLS skorları, troponin, D-dimer değerleri, Ekokardiyografi (EKO) bulguları incelendi. Epworth, Berlin, STOP, STOP-BANG uyku anketleri açısından yüksek ve düşük riskli hasta grupları PTE parametreleri açısından karşılaştırıldı. Bulgular: Hastaların 138’inde (%69,6) Berlin, 174’ünde (%87,8) STOPBANG, 152’sinde (%76,7) STOP anketi, 127’sinde (%64,1) Epworth anketi yüksek riskli olarak saptandı. Berlin skoru ile kalp yetmezliği, PESİ ve SPESİ skoru, troponin değerleri arasında; Epworth skoru ile WELLS skoru arasında; STOP-BANG skoru ile PESİ skoru arasında istatiksel olarak anlamlı bir ilişki bulundu (p<0,05). Bir aylık takip süresinde hastalardan dokuzu eksitus olup mortalite %4,5 saptandı. Sonuç: PTE tanılı hastalarda OUAS prevalansını ve gündüz aşırı uyku halini sıklığını normal popülasyona göre artmış bulduk. Çalışmamızın sonucu olarak OUAS’ın PTE için bir risk faktörü olabileceği düşünüldü. OUAS PTE şiddetini ve prognozunu ağırlaştırabildiği gösterildi
Correlation between Pulmonary Embolism and Sleep Apnea
Introduction: It has been shown that there is a correlation between Obstructive Sleep Apnea Syndrome (OSAS) and pulmonary thromboembolism (PTE); OSAS is a risk factor for PTE. We aimed to evaluate the frequency of OSAS in PTE patients, the correlation of OSAS with the severity of PTE, and its effect on 1-month mortality in PTE patients. Methods: This single-center, prospective, comparative case control study contains 198 patients diagnosed with non-massive PTE in our hospital between the dates of 01/07/2018–04/01/2020 who were confirmed by imaging methods. Daytime sleepiness was assessed with Epworth questionnaires, and OSAS risk was assessed with Berlin, STOP, STOPBANG sleep questionnaires. Alongside demographic and clinical data, comorbidities, Pulmonary Embolism Severity Index (PESI), simplified PESI (sPESI), WELLS scores, troponin, D-dimer values, echocardiyography (ECHO) findings were also examined. Epworth, Berlin, STOP, STOP-BANG sleep groups were compared in terms of PTE parameters. Results: A hundred and thirty-eight patients (69.6%) was assesed as high risk group according to Berlin, meanwhile STOP-BANG defined 174 patients (87.8%), furthermore STOP has considered 152 patients in the high risk group (76.7%) and Epworth questionnaire determined this number as 127 (64.1%). As a result of the logistic regression analysis, statistically significant correlation was found between Berlin score and heart failure, PESI, sPESI and troponin values; between Epworth score and WELLS score; between STOP-BANG score and PESI score (p<0.05). During the 1-month follow-up period, 9 of the patients were exitus and mortality was 4.5%. Conclusion: OSAS risk is more common in patients with PTE and it may be a risk factor for PTE. It has been shown that the risk of OSAS may aggravate PTE severity and prognosis

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