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Yıl:2023; Cilt: 60; Sayı: 2>> Özet
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Nöropsikiyatri Arşivi; 2023;60(2):129-133
Epilepsi Hastalarının Kognitif İşlevlerinin Dijital Nöropsikolojik Değerlendirilmesi
A Feyzioğlu, İ Midi, E Ayık, G B Kaşıkçı, C Kaşıkçı
Sağlık Bilimleri Üniversitesi, İstanbul
Amaç: Kognitif bozukluk sıklıkla epilepsiye sekonder olarak ortaya çıkmaktadır. Bu çalışma, idiyopatik jeneralize epilepsi (İJE) hastalarının kognitif işlevlerini dijital nöropsikolojik değerlendirme ile ele almayı amaçlamaktadır. Yöntem: Kliniğimizde son 10 yılda İJE tanısı almış ve en az sekiz yıllık eğitimini tamamlamış 79 hasta çalışmaya alındı. Otuz altı sağlıklı ve 36 İJE sendromu tanılı, 18–48 yaşları arasındaki bireyler, çalışmaya katılma kriterlerini karşıladı. Tüm gönüllü katılımcılara standardize mini mental test (SMMT) ve Beck depresyon ölçeği (BDÖ) uygulandı. Nörokognitif değerlendirme için katılımcılar çeşitli kognitif alanları değerlendiren TestMyBrain (TMB) dijital nöropsikolojik test bataryasının (DNT) TMB sayı menzili, TMB seçici tepki hızı testi, TMB görsel çağrışım çiftleri testi, TMB matris akıl yürütme ve TMB sayı sembol eşleştirme testi olmak üzere beş testini tamamladı. Bulgular: İdiyopatik jeneralize epilepsi hastalarının dikkat, kısa süreli bellek, çalışma belleği, görsel bellek, epizodik bellek, kognitif işlemleme hızı, seçici tepki/inhibisyon, akıcı kognitif beceri ve algısal akıl yürütme alanlarında kognitif işlevselliği daha kötü bulundu. Sonuçlar, İJE hastalarının birçok alanda kognitif işlev bozukluğuna sahip olduğunu göstermektedir. Sonuç: IJE hastaları, TMB’nin bazı testlerinde anlamlı olarak daha kötü performans göstermiştir. Bu çalışmada, epilepsi hastalarının nöbetlerini kontrol altına almak için sadece semptomatik tedavi vermenin yanı sıra, işlevselliklerinde büyük önem taşıyacak kognitif yönlerinin değerlendirilmesi gerekliliği vurgulanmaktadır
Digital Neuropsychological Assessment of Cognitive Functions in Patients with Epilepsy
Introduction: Cognitive impairment often occurs secondary to epilepsy. This study aims to evaluate the cognitive functions of patients with idiopathic generalized epilepsy (IGE) by using the digital neuropsychological assessment. Methods: Seventy-nine patients diagnosed with IGE in the last 10 years in our clinic, who completed at least eight years of education were recruited. Participants who met the criteria were 36 individuals with IGE syndrome as well as 36 healthy individuals between the ages of 18–48. All volunteer participants were administered the standardized mini mental test (SMMT) and the Beck depression scale (BDS). For the neurocognitive assessment, participants completed five tasks in TestMyBrain digital neuropsychology test battery (TMB) which are TMB digit span, TMB choice reaction time test, TMB visual paired associates test, TMB matrix reasoning, and TMB digit symbol matching assessing a variety of cognitive domains. Results: IGE patients showed lower cognitive performance in attention, short-term memory, working memory, visual memory, episodic memory, cognitive processing speed, response selection/inhibition, fluid cognitive ability, and perceptual reasoning domains. The results show that IGE patients have cognitive dysfunction in many cognitive domains. Conclusion: IGE patients performed significantly worse outcomes in some tests of the TMB. In this study, it is aimed to emphasize the necessity of evaluating the cognitive aspects of epilepsy patients, which will be of great importance in their functionality, in addition to providing symptomatic treatment in order to control their seizures.

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