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Yıl:2023; Cilt: 30; Sayı: 2>> Özet
TAM METİN
Çocuk ve Gençlik Ruh Sağlığı Dergisi; 2023;30(2):123-127
Otizm Spektrum Bozukluklarının Doğum Mevsimi ile İlişkisinin İncelenmesi
R Bodur, M B Usta
Ondokuz Mayıs Üniversitesi , Samsun
Amaç: Doğum mevsimi, D vitamini eksikliği ve maternal enfeksiyonların otizm spektrum bozukluklarının (OSB) patogenezinde rol oynadığı ileri sürülmektedir. Mevcut verilerde tutarsızlıklar olmakla beraber ülkemizde OSB ile doğum mevsimi ilişkisini inceleyen çalışmalar kısıtlıdır. Bu çalışmada, OSB ile doğum mevsimi arasındaki ilişkinin araştırılması amaçlanmıştır. Gereç ve Yöntem: Çalışma örneklemi Ocak 2006- Ekim 2020 arasında Ondokuz Mayıs Üniversitesi (OMÜ) Çocuk Psikiyatri Polikliniği'ne başvuran OSB tanısı konmuş, 0-18 yaş arasındaki 1.523 olgudan oluşmaktadır. Hastalar retrospektif olarak Nucleus® poliklinik sistemi ile taranmıştır. Sistemden hastaların doğum tarihi, ilk başvuru tarihi, başvuru tanısı, toplam başvuru sayısı, tanı yaşı ve cinsiyet bilgilerine ulaşılmıştır. Veriler SPSS v22.0 ile analiz edilmiştir. Bulgular: 2006-2020 yılları arasında OMÜ Çocuk Psikiyatrisi polikliniğine başvuran OSB tanısı almış toplam 4.001 başvuru bulunmuş olup bunların 1.523 farklı hastaya ait olduğu tespit edilmiştir. Hastaların polikliniğe ilk başvuru yaşları ortalama 72,9 ay olarak belirlenmiştir. En sık ilk başvuru 37. aydaydı. Toplamda başvuran 1.523 hastanın %75,3’ü (n=1.147) erkek, %24,7’si (n=376) kızdır. Yıllara göre başvuru sayısına bakıldığında 2006-2015 yılları arasında başvuru sayısındaki lineer artış dikkati çekmektedir. Doğum mevsimleri analiz edildiğinde sonbahar doğumlarının istatistiksel olarak anlamlı yüksek (χ²: 19.763, p=0.001) olduğu gözlendi. Sonuç: Çalışmamızda OSB ile doğum mevsimi arasında anlamlı bir ilişki saptanmıştır. Doğum mevsimselliğinin kıyaslamak için daha büyük veri gruplarında, viral enfeksiyonlar, D vitamini seviyesi, annenin metabolik durumu gibi diğer karıştırıcı faktörlerin de incelendiği daha kapsamlı araştırmalara ihtiyaç vardır
Evaluation of The Relationship Between Autism Spectrum Disorders and Season of Birth
Objectives: It has been suggested that the birth season, vitamin D deficiency and maternal infections play a role in the pathogenesis of autism spectrum disorders (ASD). Although there are inconsistencies in the available data, studies examining the relationship between ASD and the birth season are limited in our country. In this study, it was aimed to investigate the relationship between ASD and the birth season. Materials and Methods: The study sample consisted of 1,523 cases between the ages of 0-18 who were diagnosed with ASD who applied to the Ondokuz Mayis University (OMU) Child Psychiatry outpatient clinic between January 2006 and October 2020. The patients were screened retrospectively with the Nucleus® Outpatient Clinic system. Information on the birth date, first application date, application diagnosis, total number of applications, age of diagnosis and gender were obtained from the system. Data were analyzed with SPSS v22.0. Results: A total of 4,001 applications diagnosed with ASD to the OMU Child Psychiatry outpatient clinic between 2006 and 2020 were found to belong to 1,523 individual patients. The mean age at first admission to the outpatient clinic was determined as 72.9 months. The most frequent first application was at 37 months. Of the 1,523 patients who applied in total, 75.3% (n=1,147) were male and 24.7% (n=376) were female. Considering the number of applications by years, the linear increase in the number of applications between 2006 and 2015 draws attention. When the birth seasons were analyzed, it was observed that the autumn births were statistically significantly higher (?²: 19.763, p=0.001). Conclusion: In our study, a significant relationship was found between ASD and the birth season. In order to compare parturition seasonality, more comprehensive studies are needed to examine other confounding factors such as viral infections, vitamin D level, and maternal metabolic status in larger data sets.

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