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Yıl:2022; Cilt: 9; Sayı: 3>> Özet
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Türk Uyku Tıbbı Dergisi; 2022;9(3):186-189
Şizofrenide Uyku ile İlişkili Bellek Konsolidasyonu
E N Çorum
Sağlık Bilimleri Üniversitesi,İstanbul
Uyku bozuklukları birçok nöropsikiyatrik bozukluğun belirgin bir özelliğidir. Bozulmuş uyku şizofreninin de belirgin bir özelliği olmasına rağmen, şizofreninin patofizyolojisi, belirtileri ve semptomları ile ilişkisi tam olarak anlaşılamamıştır. Şizofreni hastalarında, bilişsel işlev bozuklukları sıklıkla görülmektedir. Uyku bozukluklarının hastalığa eşlik ederek bu temel işlev bozukluklarına katkıda bulunan önemli bir mekanizma olduğu düşünülmektedir. Bu derlemede, şizofreni hastalarında uykuya bağlı bellek konsolidasyonu arasındaki ilişki araştırılmıştır. Bu doğrultuda, uykunun nörobiyolojisi, bellek süreçleri, sağlıklı bireylerde uykuya bağlı bellek konsolidasyonu, şizofrenide uykuya bağlı bellek konsolidasyonu gözden geçirilmiştir.
Sleep-related Memory Consolidation in Schizophrenia
Sleep disturbances are a prominent feature of many neuropsychiatric disorders. Although disturbed sleep is also a prominent feature of schizophrenia, its relationship with the pathophysiology, signs and symptoms of schizophrenia is not fully understood. Cognitive dysfunctions are frequently observed in patients with schizophrenia. It is thought that sleep disorders are an important mechanism that contributes to these basic dysfunctions by accompanying the disease. In this review, the relationship between sleep-related memory consolidation in patients with schizophrenia was investigated. Accordingly, the neurobiology of sleep, memory processes, sleeprelated memory consolidation in healthy individuals, and sleep-related memory consolidation in schizophrenia are reviewed.

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