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Yıl:1993; Cilt: 3; Sayı: 1-2>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 1993;3(1-2):58-64
Serotonerjik İlaçlara Genel Bir Bakış
İ Çifter
Gazi Üniversitesi, Ankara
10 yılı aşkın bir sürede ham anksiyete hem de depresif bozuklukların ortaya çıkışında serotonin sisteminin rolüne ilişkin artan bir ilgi vardır. Araştırmalar serotonin veya noradrenerjik sistemlerde geri alım blokajı için selektif terapstik bileşiklerin elde edilmesini sağlamıştır. Selektif serotonin geri alım inhibitörlerinin (SGI) panik bozukluk, obsesif kompulsif bozukluk, depresyon bozuklukları, madde kötüye kullanımı bozukluklarının tedavisinde etkili oldukları gösterilmiştir.
Selective Serotonin Reuptake Inhibitors: An Overview
Over the past decade there has been a crescendo of interest in the role of the serotonin system in mediating both anxiety and depressive disorders. Researchs has provided therapeutic compounds that are selective for re-uptake blockade in the serotonin or noradrenergic systems. The selective serotonin re-uptake inhibitors (SSRIs) have demonstrated their effectivity in the treatment of depression and obsessive-compulsive disorder, panic disorder and substance abuse disorder.

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