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Yıl:2022; Cilt: 29; Sayı: 1>> Özet
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Çocuk ve Gençlik Ruh Sağlığı Dergisi; 2022;29(1):47-49
DEHB Tedavisinde Atomoksetin ile Tetiklenen Tikler: Olgu Sunumu
M Sarı, G G Özcan, Y A İmrek, Y Öztürk, A E Tufan
Sağlık Bilimleri Üniversitesi, İstanbul
Dikkat eksikliği hiperaktivite bozukluğu (DEHB) çocuk ve ergenlerde en sık görülen nörogelişimsel bozukluklardan biri olup temel belirtileri dikkat eksiliği, aşırı hareketlilik ve dürtüselliktir. Atomoksetin DEHB tedavisinde etkinliği kanıtlanmış bir selektif noradrenalin geri alım inhibitörüdür. Gastrointestinal problemler, uyku problemleri, irritabilite, yorgunluk gibi yan etkilerinin olduğu bilinmekle beraber atomoksetin aynı zamanda tik bozukluğu da olan DEHB’li çocuk ve ergenlerde sıklıkla tercih edilmektedir. Ancak literatürde atomoksetin tedavisi sırasında tikleri başlayan veya var olan tikleri şiddetlenen az sayıda hasta bildirilmiştir. Bu olgu sunumunda DEHB tedavisi için atomoksetin kullanan ve tedavi ile tikleri tetiklenen 7 yaşında bir çocukta bu yan etkinin mekanizması tartışılmıştır.
Atomoxetine Induced Tics in ADHD Treatment: A Case Report
Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children and adolescents and its main symptoms are attention deficit, hyperactivity and impulsivity. Atomoxetine is a selective noradrenaline reuptake inhibitor with proven efficacy in the treatment of ADHD. Although it is known that it has side effects such as gastrointestinal problems, sleep problems, irritability and fatigue, atomoxetine is frequently preferred in children and adolescents with ADHD who also have tic disorder. However, a small number of patients whose tics started or worsened during atomoxetine treatment have been reported. In this case report, we discussed the mechanism of this adverse effect in a 7-year-old child who used atomoxetine for ADHD treatment who had treatment related triggering of tics.

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