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Yıl:1991; Cilt: 1; Sayı: 3>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 1991;1(3):69-70
Şizofrenik Bozukluklarda Sulpirid Kullanımı
E Aktener, R Saygılı
Ege Üniversitesi, İzmir
Selektif tip-2 dopamin reseptör antagonisti olan sulpiride, benzamide ailesinden orijinal bir bileşimdir. Depresif, stimulan, otonomik ve kardiyovasküler etkilerinin olmadığı, diğer nöroleptiklere kıyasla daha az ekstrapiramidal bozukluğa neden olduğu ileri sürülmektedir. Bu makalede şizofrenik bozukluklarda kullanımı gözden geçirilmiştir.
The Use of Sulpiride in Schizophrenic Disorders
Sulpiride is a member of the substituted benzamide group of drugs. It has a selective type-2 dopamine receptor antagonist Claims have been made that it does not cause significant depressive, stimulant, autonomic or cardiovascular effects, and produces less extrapyramidal disturbance than other neuroleptics. In this article the use of sulpiride in schizophrenic patients was reviewed.

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