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Yıl:2021; Cilt: 32; Sayı: 3>> Özet
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Türk Psikiyatri Dergisi; 2021;32(3):151-159
Şizofrenide 10 Yıllık Ölüm Oranı ve Risk Etmenlerinin Değerlendirmesi
H Yaşar, M Yıldız
Kocaeli Üniversitesi, Kocaeli
Amaç: Çalışmada şizofrenisi olan hastaların 10 yıllık takip süresindeki ölüm oranı ve risk etmenlerinin saptanması amaçlandı. Yöntem: Bir üniversite kliniğinde 2004-2008 yılları arasında ayaktan ya da yatarak tedavi gören şizofreni tanılı hastalar 2018 yılı sonunda ölüm ve sağkalım açısından kontrol edildi. Aynı dönemde toplumdaki ölüm oranıyla karşılaştırıldı. Ölüm açısından risk etmenleri incelendi. Bulgular: Kayıtlı olan 626 hastanın 506’sı çalışmaya alındı. Ölüm oranı %10,6, ölüm yaş ortalaması 53,1 bulundu. Tüm hastalarda beklenen yaşam süresi 73,4 yıl (erkeklerde 66,6, kadınlarda 77,6, sigara içenlerde 64,7, içmeyenlerde 76,5) idi. Standart ölüm hızı 3,7 (erkeklerde 3,9, kadınlarda 3,3) olarak hesaplandı. Ölüm için risk etmenleri olarak ileri yaş, erkek cinsiyet, sigara içimi, çalışmama ve hastalığın erken başlaması bulundu. Sonuç: Sigara içimi ölüm riskleri arasındaki önemli bir yer tutuyor. Önlenebilir risk etmeni olarak sigarayı bırakmaya yönelik programlara öncelik verilmesi ve hastaların çalışma yaşamında yer almasını sağlayacak iyileştirim çalışmalarının yapılması şizofrenide ölüm riskini azaltan girişimler olabilir.
Assessment of Mortality Rate in 10 Years and the Associated Risk Factors in Schizophrenia
Objective: The aim of the study was to explore the mortality rate and the associated risks factors in patients with schizophrenia during a10- year follow up period. Method: We searched the records of patients with schizophrenia receiving treatment as outpatients and/or inpatients in the psychiatric clinic of a university hospital between 2004 and 2008 and determine the survival of these patients by the end of 2018. The results were compared with the all cause mortality rate in the general population during the same period. Also, the risk factors affecting the mortality rate among the patients were investigated. Results: Out of a total of 626 registered patients 506 were included in the study. The mortality rate within 10 years was found to be 10.6%, with a mean age of 53.1 years at the time of death. The overall expected life expectancy was 73.4 years; varying between 66.6 years among the males and 77.6 years among the females; and 64.7 and 76.5 years among smokers and non-smokers, respectively. The overall standardized mortality rate (SMR) was 3.7, being 3.9 among the males and 3.3 among the females. The risk factors that were associated with the death were old age, male gender, smoking, not working, and early age of disease onset. Conclusion: Smoking is a significant risk factor for mortality. Giving priority to programs for stopping smoking, and supporting rehabilitation services that enables patients to get involved in could help reducing the mortality risk.

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