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Yıl:2021; Cilt: 58; Sayı: 3>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2021;58(3):193-199
Obsesif Kompulsif Bozuklukta Mevsimsel Değişiklikler: Prospektif-Klinik Veri Analizi
E Altıntaş, MÖ Kütük, AE Tufan
Başkent Üniversitesi, Adana
Amaç: Az sayıda çalışma anksiyete semptomlarının şiddetinde olası mevsimsel değişiklikleri araştırmıştır. Bu araştırma, Obsesif Kompulsif Bozukluk (OKB) tanılı hastalarda mevsimsel değişikliklerin obsesif ve kompulsif semptomların şiddetini etkileyip etkilemediğini değerlendirmeyi amaçlamıştır. OKB hastalarındaki anksiyete ve depresyon belirtileri ve mevsimler arasındaki ilişki de araştırılmıştır. Bunun yanında, hastaların bildirimlerine dayanan retrospektif veriler ile prospektif gözlemle elde edilen veriler arasındaki farklar da karşılaştırılmıştır. Yöntem: Yale-Brown Obsesyon Kompulsiyon Ölçeği (Y-BOCS), Y-BOCS Belirti Kontrol Listesi, Beck Anksiyete Ölçeği ve Beck Depresyon Ölçeği OKB tanılı 148 hastaya bir yıl içinde her mevsimde uygulanmıştır. Mevsim ve ölçekler arasındaki ilişkiler hastaların retrospektif gözlemlerine dayanarak, ve yıl boyunca toplanan prospektif verilere göre analiz edilmiştir. Farklı mevsimlerde alınan ölçek puanları karşılaştırılmıştır. Bulgular: Obsesif ve kompulsif semptomların şiddeti mevsimsel değişiklik göstermemiştir. Çok düzeyli büyüme modelleri bu semptomlardaki mevsimsel değişimin öznel olarak bildirilen anksiyete ve depresyon semptomları ve bunların etkileşimi ile açıklanabileceğini düşündürmüştür. Önemli olarak, yapılandırılmış klinik ölçeklerden yapılan prospektif gözlemler kullanılarak elde edilen sonuçlar, hastaların retrospektif gözlemleri kullanılarak elde edilenlerden farklıdır. Sonuç: Çalışmamız OKB belirtilerinde mevsimsel değişikliklerin varlığını desteklememektedir. OKB belirtilerindeki mevsimsel değişiklikleri tanımlamak için ileri çalışmalara ihtiyaç vardır.
Seasonal Variations in Obsessive-Compulsive Disorder: Analysis of Prospective-Clinical Data
Introduction: Few studies have investigated potential seasonal changes in anxiety disorders. This study aimed to evaluate whether seasonal changes influence the severity of obsessive and compulsive symptoms in obsessive-compulsive disorder (OCD). The relationship between comorbid anxiety and depression symptoms and the seasons was also investigated. Furthermore, we compared the differences between retrospective data reliant on patients’ recall and data obtained by prospective observation. Methods: The Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Y-BOCS Symptom Checklist, Beck Anxiety Scale, and Beck Depression Scale were administered to 148 patients with OCD in each of the four seasons over a year. The relationships between the seasons and the scales based on retrospective observations of the patients, and between the seasons and scales based on prospective data collected over the year were analyzed. Scores from clinical assessments were compared between the different seasons. Results: The severity of obsessive and compulsive symptoms, did not show seasonal changes. Multi-level growth models suggested that the change in Y-BOCS Total scores across seasons could be explained by subjective symptoms of depression and anxiety and their interactions. Importantly, results obtained using prospective observations from structured clinical assessment differed from those obtained using retrospective observations of patients. Conclusions: Our study does not support the existence of seasonal variations in symptoms of OCD. Future studies are needed to delineate seasonal variations in OCD symptoms.

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