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Yıl:2005; Cilt: 15; Sayı: 4>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 2005;15(4):192-197
Dikkat Eksikliği Hiperaktivite Bozukluğu Psikofarmakolojisinde Yeni Gelişmeler
C Şengül, CB Şengül, EÖ Kılıç, N Dilbaz
Ankara Numune Hast. 2. Psikiyatri Kliniği
DEHB (Dikkat Eksikliği Hiperaktivite Bozukluğu] farmakoterapisi uzun zamandır d-amfetamin ve metilfenidat gibi stimulan ilaçlarla yapılmaktadır. Trisiklikantidepresanlar da stimulan ilaçlarla karşılaştırabilir ölçüde etkilidirler. Bu ilaçlar DEHB tedavisinde 30 yıldan fazla süredir kullanılmaktadır. Ancak bu ilaçların yan etkileri ve stimulan ilaçların kısa yarı ömrü DEHB tedavisinde kullanımlarını kısıtlamaktadır. Son yıllarda DEHB tedavisinde birçok ilaç geliştirilmiştir. Bunlar uzun etkili stimulanlar, atomoxetine ve yeni antidepresan ilaçlardır. Bunlar dışında antihipertansifler gibi bazı ilaçlar da DEHB tedavisinde denenmiş ve etkili bulunmuşlardır. Biz bu yazımızda DEHB farmakoterapisinde yeni gelişmeleri gözden geçirdik.
Recent Advances In The Psychopharmacology Of Attention Deficit Hyperactivity Disorder
Pharmacotherapy of ADHD (Attention Deficit Hyperactivity Disorder)
has largely been conducted with stimulant compounds such as
d-amphetamine and methylphenidate. Tricyclic antidepressants are
also reported to be as effective as stimulants. They have been used
for ADHD treatment more than 30 [year]s. But side effects and short
half life of stimulants limit their usage in treatment for ADHD. In recent
[year]s many novel compounds have been developed for ADHD
treatment. These are long acting stimulants, atomoxetine and novel
antidepressant drugs. There are also some other drugs like
antihypertensives said to be effective in the treatment of ADHD. In this
article recent advances in the pharmacotherapy of ADHD have been
reviewed.

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