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Yıl:2019; Cilt: 56; Sayı: 3>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2019;56(3):229-231
Yeni Bir Psikoaktif Madde, Gama Hidroksibütirat (GHB): Bir Olgu Sunumu
H Bulut
SBÜ Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi, İstanbul
Gama hidroksibütirat (GHB), etkisini GABA-B reseptörleri üzerinden gösteren bir santral sinir sistemi depresanıdır. Parti ortamlarında alkol, ekstazi, kokain, amfetaminler gibi diğer psikoaktif maddelerle birlikte kullanılabilmektedir. GHB, son yıllarda özellikle cinsel saldırılarda kullanılması nedeniyle dikkatleri üzerine çekmiştir. Kendini mutlu hissetme, rahatlama, sosyal iletişimde kolaylık, cinsel istekte artış, farklı bilinç hallerini yaşama isteği gibi nedenlerle özellikle de gençler arasında sıkça kullanılmaktadır. Tipik zehirlenme belirtileri arasında sersemlik, hipotansiyon, bradikardi, bulantı, kusma sayılmaktadır. Epileptik nöbet, solunum depresyonu ve ölümle sonuçlanan durumlar da bildirilmiştir. Ülkemizde de GHB kullanımının giderek artış gösterdiği bilinmektedir. Olgu sunumumuz, yeni bir psikoaktif madde olan GHB’nin anamnez bilgileri, kullanım yaygınlığı ve klinik belirtilerini özetlemesi nedeniyle önemlidir. Sonuç olarak, GHB kullanımının önlenmesi için psikoeğitim yaklaşımlarının geliştirilmesi, yasal düzenlemelerin yapılması ve madde tarama testleri içerisine GHB’nin de alınması uygun olacaktır.
A New Psychoactive Substance, Gamma Hydroxybutyrate (GHB): A Case Report
Gamma Hydroxybutyrate (GHB) is a central nervous system depressant effecting GABA-B receptors. GHB is taken along with other psychoactive substances like alcohol, cocaine, ecstasy, and amphetamines especially during parties. Due to the fact that it has been linked to sexual assault, GHB has drawn attention in recent years. This substance is often taken by youngsters and results in euphoric states of mind, signs of relief, easiness in communication, increases in sexual appetite, and experiences of different states of mind. Dizziness, hypotension, bradycardia, nauseation, and vomiting are typical toxication symptoms of GHB. Also, epileptic seizures, respirotary depression, and deaths have been reported as a result of taking GHB. It is widely known that the use of GHB in our country has increased gradually. This case report is important as it summarizes the anamnesis, penetration, and clinical symptoms of GHB. In order to prevent the use of GHB, it would be appropriate to develop psycho-education methodologies, establish legislative regulations, and include GHB tests in substance screening analyses.

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