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Yıl:2019; Cilt: 56; Sayı: 3>> Özet
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Nöropsikiyatri Arşivi; 2019;56(3):213-218
Remisyon Dönemindeki İki Uçlu Bozukluk Hastalarının İşlevsellik Düzeylerive İlişkili Faktörlerin Değerlendirilmesi
Y Hacımusalar, ES Doğan
Yozgat Bozok Üniversitesi, Yozgat
Amaç: İki uçlu bozukluk, alevlenme ve iyileşme dönemleri ile seyreden bir hastalıktır. İyileşme döneminde semptomlarda büyük oranda hatta bazen tama yakın düzelme görülse bile hastaların işlevsellik düzeyleri hastalık öncesi döneme göre düşük seyredebilmektedir. Bu çalışmada remisyon döneminde olan iki uçlu bozukluk (İUB) hastalarının işlevsellik düzeylerinin sağlıklı kontrollerle karşılaştırılması ve işlevsellikle ilişkili faktörlerin değerlendirilmesi amaçlanmıştır. Yöntem: Bu kesitsel çalışmada üç ay veya daha uzun süredir remisyon döneminde olan İUB-I hastaları ile sağlıklı kontrol grubunun işlevsellik düzeyleri karşılaştırılmıştır. Çalışmada remisyon durumunu belirlemek için Young Mani Derecelendirme Ölçeği ve Hamilton Depresyon Derecelendirme Ölçeği, işlevsellik düzeyini belirlemek için de Bipolar Bozuklukta İşlevsellik Ölçeği (BB-İ) kullanılmıştır. Bulgular: Çalışmaya remisyon döneminde olan 165 İUB hastası ve 63 sağlıklı kontrol alınmıştır. Hasta ve kontrol grubunun işlevsellik düzeyleri BB-İ ile karşılaştırıldığında hastaların zihinsel işlevsellik, cinsel işlevsellik, damgalanma hissi, içe kapanıklık, arkadaşlarıyla ilişkileri, toplumsal etkinliklere katılım, günlük etkinlikler ve hobiler, inisiyatif alma alanlarındaki işlevsellikleri kontrol grubuna göre anlamlı derecede düşük bulunmuştur. Hastalar kullandıkları ilaçlara göre işlevsellik açısından karşılaştırıldığında; duygudurum dengeleyiciye ek olarak en az bir tane antipsikotik kullananların ev içi işlevselliği ve içe kapanıklık alanındaki işlevsellikleri sadece duygudurum dengeleyici kullanan hastalara göre anlamlı derecede bozuk bulunmuştur. Sonuç: İUB’de remisyon dönemlerinde bile işlevselliğin birçok alanında bozulma görülmektedir. Bu hastaların tedavilerinde farmakolojik tedavi ile remisyonun hedeflenmesi yanında işlevselliğe yönelik psikososyal müdahalelerde de bulunulması önemlidir
Assessment of the Functioning Levels and Related Factors in Patients with Bipolar Disorderduring Remission
Introduction: The course of bipolar disorder (BD) is characterized by relapse and remission periods. Although the symptoms show a significant and sometimes almost complete improvement during remission, the patients’ functioning levels may be lower compared to the premorbid period. This study aimed to compare the functional levels between patients with BD during remission period and healthy controls and to evaluate the factors related to the functional status of the patients. Methods: In this cross-sectional study, functioning levels of the BD-I patients, who were in remission for three months or longer, were compared with those of the healthy controls. Young Mania Rating Scale and Hamilton Depression Rating Scale were used to determine remission status, and Bipolar Disorder Functioning Questionnaire (BDFQ) was used to determine the level of functioning. Results: The study included 165 BD-I patients during remission and 63 healthy controls. The BDFQ scores of the patients including intellectual functioning, sexual functioning, feeling of stigmatization, introversion, relationships with friends, participation in social activities, daily activities and hobbies, and taking initiative were found to be statistically significantly lower than those of the controls. When the functioning comparisons were carried out within the patients considering the drugs they were using, the functioning levels including domestic functioning and introversion domains were found to be significantly impaired in those who use at least one antipsychotic in addition to the mood stabilizers than in those who use only mood stabilizers. Conclusion: In BD, the impairments within multiple functioning domains are observed even during remission periods. Besides targeting remission through pharmacological treatment, psychosocial interventions for functioning are also important in the treatment of these patients

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