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Yıl:2019; Cilt: 56; Sayı: 3>> Özet
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Nöropsikiyatri Arşivi; 2019;56(3):178-181
Psikojen Non-Epileptik Nöbet Semiyolojisinde Cinsiyet ile İlişkili Farklılıklar
HS Türe, I Tatlıdil, E Kılıçarslan, G Akhan
İzmir Katip Çelebi University , Izmir
Amaç: Bu çalışmanın amacı, psikojen non-epileptik nöbetlerin (PNEN) semiyolojisindeki cinsiyete bağlı farklılıkları saptamaktır. Yöntem: Bu retrospektif çalışmaya 2010–2017 yılları arasında video EEG (elektroensefalografi) monitorizasyon ile PNEN tanısı alan, 13–67 yaşları arasında 155 hasta (erkek:kadın=63:92) dahil edildi. Hastalar cinsiyetlerine göre gruplandırıldı. Olgular video EEG ile PNEN’in birincil semiyolojik özellikleri açısından standardize edildi. İstatiksel analizlerde Ki-kare testi ve Fisher exact testi kullanıldı. Bulgular: Kadınlarda daha sık gözlenen PNEN’in 20 ila 23 yaşları ve 40–43 yaşlarında arasında iki pik yaptığı saptandı. Majör motor aktivite (p=0,032), lateralize motor aktivite (p=0,017) ve opistotonik postürpelvik itme hareketi (p=0,017) erkeklerde anlamlı olarak daha sık iken, ağlama (p<0,001) kadın cinsiyet ile anlamlı olarak ilişkili bulundu. Sonuç: Çalışmamız PNEN’de cinsiyetler arasında bazı semiyolojik farklılıklar olduğunu göstermiştir. Erkek hastalarda lateralize motor bulguların daha ön planda olması ve nöbetlerde iktal ağlamanın eşlik etmemesi epileptik nöbetler ile daha çok karışmasına neden olur. Erken ve doğru tanı için PNEN’de semiyolojik özelliklerin iyi bilinmesi önemlidir.
Gender-Related Differences in Semiology of Psychogenic Non-EpilepticSeizures
Introduction: The aim of the study is to detect possible gender-related differences in the semiology of psychogenic non-epileptic seizures (PNES). Methods: One hundred fifty-five patients (male: female=63:92) aged 13 to 67 years, who were diagnosed with PNES by video-monitoring electroencephalogram (EEG) between 2010 and 2017, were included in this retrospective study. Patients were grouped according to their gender. The primary semiological characteristics of PNES for each case were defined, standardized, and categorized by an epileptologist during video-monitoring EEG. The chi-square test and the Fisher exact test were used statistically. Results: An age histogram showed peaks at ages 20 to 23 and at ages 40 to 43, which were more prominent in the female gender. Whereas major motor activity (p=0.032), lateralizing motor activity (p=0.017), and opisthotonic posture and pelvic thrust motion (p=0.017) were significantly related to the male gender, weeping (p<0.001) was significantly related to the female gender. Conclusion: Our study showed that there are some semiological differences between the genders in PNES. In male patients, lateralized motor findings are more prominent and not accompanied by ictal crying in seizures, which may lead to further confusion with epileptic seizures. It is important to know the semiological characteristics for early and accurate diagnosis.

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