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Yıl:2019; Cilt: 6; Sayı: 1>> Özet
TAM METİN
The Journal of Neurobehavioral Sciences; 2019;6(1):44-48
Agarofobili ve agarofobisiz panik bozukluğu hastalarının karşılaştırılması ve agarofobinin panik bozukluğu üzerine klinik etkisi
TD Berkol, YE Yıldırım, HY Çengel, AŞ Tav, Z Özarslan, H Erensoy
Bakırköy Ruh Sağlığı ve Sinir Hastalıkları, İstanbul,
Panik Bozukluğu (PB) kendiliğinden ve beklenmedik panik nöbetleri ile giden bir anksiyete bozukluğudur. Panik ataklarının diğer hastalıklara eşlik etmesinin bu hastalıklardaki tedavi yanıtını olumsuz yönde etkilemekle beraber semptom şiddetini, komorbidite oranlarını ve intihar riskini arttırdığı da gösterilmiştir. Agorafobi, kaçınmanın güç olabileceği ya da panik nöbet halinde yardımın gelemeyebileceği yerler ya da durumlarda bulunmaktan korku duymaktır. Agorafobi ile PB ilişkisinin hastalık sürecine yönelik etkisi üzerine yapılan çalışmalarda Agorafobinin eşlik ettiği PB hastalarında hastalık başlangıç yaşının daha erken, epizodların daha uzun, belirtilerin daha şiddetli, eştanıların ve kronikliğin daha sık olduğu ve genel olarak prognozun daha olumsuz seyrettiği gösterilmiştir. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi psikiyatri polikliniğini ziyaret eden 100 hasta başta sadece PB veya agorafobili PB olarak tanı almıştır. Agorafobili olan PB grubunda KGİ, İGD, BECK-A puanları agorafobi olmadan PB grubundan anlamlı olarak daha olumsuz sonuçlar göstermekteydi. Buna karşılık iki grubun BECK-D puanları ise benzerdi. Ayrıca agorafobili olan grupta ortalama PAÖ toplam puanı ile panik atağı özellikleri, agorafobi/kaçınma davranışı, beklenti anksiyetesi, yeti yitimi ve sağlık konusunda endişe alt başlıkları puan ortalamaları da karşılaştırma grubuna göre daha yüksekti. Bizim çalışmamızda örneklem PB hastalarından oluşmakta olup PB’na eşlik eden Agorafobi sıklığı %44 olarak belirlenmiştir. Bu çalışmada agorafobi ile birlikte olan ve olmayan panik bozukluğu hastalarının sosyodemografik ve klinik özelliklerinin karşılaştırılması amaçlanmıştır.
Comparison of patients with and without agoraphobia panic disorder and the clinical effect of agoraphobia on panic disorder
Panic Disorder (PD) is an anxiety disorder characterized by spontaneous and unexpected panic attacks. Agoraphobia is the fear of being in a place or setting where escaping or receiving help may be difficult in case of a panic attack. Studies on the effect of the relationship between agoraphobia and PD on the disease process have shown that patients with PD accompanied by agoraphobia have earlier disease onset, more severe symptoms, a higher rate of comorbidity and chronicity, and a more negative prognosis in general. The purpose of this study was to compare sociodemographic and clinical characteristic of panic disorder patients with and without agoraphobia. The sample of the study consists of 100 patients who have applied to the psychiatry clinic of the Lutfi Kirdar Kartal Training and Research Hospital and who have been diagnosed with only PD or PD with agoraphobia by clinical interview (SCID-I) based on the DSM-IV. The sociodemographic data form, Clinical Global Impression Scale (CGIS), Global Assessment Scale (GAS), Beck Depression Inventory (BECK-D), Beck Anxiety Inventory (BECK-A), and Panic and Agoraphobia Scale were used for all patients. The incidence of agoraphobia accompanying PD was found to be 44% in our study. The PD with agoraphobia group had significantly worse results compared to the PD without agoraphobia group in terms of CGIS, GAS, and BECK-A scores. Also, the PD with agoraphobia group had a higher mean total PAS score and higher mean agoraphobic avoidance, anticipatory anxiety, disability, and functional avoidance (health concerns) sub-scale scores.

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