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Yıl:2019; Cilt: 56; Sayı: 1>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2019;56(1):27-31
Dikkat Eksikliği / Hiperaktivite Bozukluğu Olan Çocuklarda Metifenidatın Reaksiyon Süresine Etkileri
A Güven, M Altınkaynak, N Dolu, E Demirci, S Özmen, M İzzetoğlu, F Pektaş
Erciyes University, Kayseri
Amaç: Dikkat eksikliği/hiperaktivite bozukluğu (DEHB), metilfenidat (MPH) tedavisi ile düzelme gözlenen bir çok nöropsikolojik bozuklukla ilişkilendirilmiştir. Bu çalışmanın amacı, MPH’ın DEHB’de dikkat işlevini nasıl etkilediğini reaksiyon süresi (RS) ile belirlemektir. Yöntem: Çalışmaya daha önce tedavi görmemiş onsekiz DEHB’li çocuk (7–12 yaş) ve on sekiz cinsiyet eşleştirilmiş sağlıklı çocuk (7–12 yaş) dahil edildi. Katılımcılara işitsel dikkat testi uygulandı ve hedef uyaranlara verdikleri reaksiyon süresi otomatik olarak hesaplandı. DEHB grubundan uzun süreli MPH ilaç tedavisinden üç ay sonra kayıtlar yeniden alındı. RS, RS standart sapması (RSSS) ve yanıt hataları (ihmal ve görev hataları) kontrol grubu ve MPH öncesi grubu arasında ve MPH öncesi ve sonrası DEHB’li grup arasında karşılaştırıldı. Bulgular: İşitsel dikkat görevi sırasında, tedavi öncesi DEHB’li grupta kontrol grubuna göre anlamlı bir şekilde daha uzun RS, daha yüksek RSSS ve daha fazla ihmal hatası gözlenmiştir. Yapılan analizler, tedavinin görev hataları dışındaki tüm ölçümlerde anlamlı etkisi olduğunu göstermiştir. Tedavi sonrası DEHB’li grupda tedavi öncesi duruma göre, anlamlı olarak RS daha hızlıydı, RSSS değerleri daha düşüktü ve ihmal hataları daha azdı. Görev hataları açısından gruplar arasında istatistiksel olarak anlamlı farklılık yoktu. Sonuç: Yapılan çalışmada, MPH’ın çocukların uyarana verdikleri reaksiyon süresini azalttığı, görev esnasında ihmal hatalarını azalttığı ve üç aylık tedavi sonrası kontrol grubuyla benzer örnekler gösterdiği gözlenmiştir. Sonuçlar, DEBH tedavisinde klinisyenlerin RS, RSSS ve yanıt hataları gibi objektif ve non-invazif kognitif çıktıları kullanmalarının, tedavinin etkilerini değerlendirmelerine yardımcı olabileceğini göstermektedir.
Effects of Methylphenidate on Reaction Time in Children with AttentionDeficit / Hyperactivity Disorder
Conclusion: In this study it was observed that MPH reduced RTs to stimuli, attenuated omission errors during the task in ADHD group and after 3 months of treatment ADHD children showed similar patterns in RT as compared to controls. Results suggest that when treating ADHD, it might help clinicians to evaluate objective and non-invasive cognitive outcomes such as RT, RTSD and response errors to evaluate the effects of treatment.

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