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Yıl:2019; Cilt: 56; Sayı: 1>> Özet
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Nöropsikiyatri Arşivi; 2019;56(1):18-22
Esansiyel Tremor Sadece Hareket Hastalığı Değildir; Uyku ve Anksiyetenin Hastalıkla İlişkisi
BA Acar, T Acar
Sakarya Üniversitesi Tıp Fakültesi, Sakarya
Amaç: Yedi LDL altsınıfı tanımlanmıştır ve daha küçük LDL altsınıfları artmış kardiyovasküler olay riski ile ilişkilidir. Ancak, akut iskemik inme subtipleri ile LDL altsınıfları arasındaki ilişkinin incelendiği veriler sınırlıdır. Çalışmamızın amacı iskemik inme subtipleri ile LDL altsınıfları arasındaki ilişkiyi incelemektir. Yöntem: Bu çalışma 110 akut iskemik inme hastası ve 60 sağlıklı kontrol grubundan oluşturuldu. İnme hastaları Trial of Org 10172 in Acute Stroke Treatment (TOAST) sınıflamasına göre kardiyoembolik infarkt (Kİ), büyük arter aterosklerozu (BAA) ve laküner infarkt (Lİ) olarak gruplara ayrıldı. LDL altsınıflarının serum konsantrasyonları LipoPrintª sistemine göre yedi banda ayrıştırıldı (LDL-1 ve LDL-2 büyük LDL olarak tanımlandı, LDL- 3’ten LDL-7’ye kadar küçük LDL partikülü olarak adlandırıldı). Kontrol grubu ve iskemik inme alttipleri, LDL altsınıfları açısından karşılaştırıldı; p değerinin <0,05 olması istatistiksel anlamlı olarak kabul edildi. Bulgular: Kontrol grubu ile karşılaştırıldığında, iskemik inme hastaları daha yüksek LDL-2, LDL-3 ve LDL-4 altsınıflarına sahiptiler, ancak LDL-1 her iki grupta da benzerdi. Ek olarak, kontrol grubu ile karşılaştırıldığında LDL2 ve DL-3 altsınıfları her bir iskemik inme alttipinde anlamlı olarak daha yüksekti. LDL-4 altsınıfı, kontrol grubuna göre BAA ve Lİ alttipinde daha yüksekti, fakat Kİ alttipi için anlamlı bir ilişki yoktu. Daha küçük LDL altsınıfları (LDL-5’ten LDL-7’ye kadar) hem hasta hem de kontrol grubunda tespit edilemedi. Regresyon analizinde; yaş, LDL-2, LDL-3 ve LDL-4 iskemik inme gelişiminin bağımsız öngördürücüsü olarak bulundu. Sonuç: Çalışmamız iskemik inme hastalarının yönetiminde LDL altsınıflarının incelenmesi önemli olabileceğini gösterdi. LDL-2, LDL-3 ve LDL-4 iskemik inme gelişiminin bağımsız öngördürücüsüdür. Bu bulgular daha geniş çalışmalarla desteklenmelidir. © All Right Reserved By N
Essential Tremor is not Only a Movement Disorder; Its Relationship with Sleep and Anxiety
Conclusion: Sleep disorder and anxiety are more common in patients with ET than in healthy individuals. We believe that more severe sleep disorders and anxiety in female and/or married patients are indicative of the psychosocial component of the disorder, and that this condition should not be overlooked and should be studied more comprehensively in this regar

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