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Yıl:2018; Cilt: 56; Sayı: 3>> Özet
TAM METİN
Yeni Symposium; 2018;56(3):20-23
Dikkat Eksikliği Hiperaktivite Bozukluğu ve Omega-3 Yağ Asidi Takviyesi: Sistematik BirDerleme
M Çöpür, S Çöpür
Istanbul Arel Universitesi, İstanbul
Amaç: Dikkat eksikliği hiperaktivite bozukluğu başlıca okul çapındaki çocukları etkileyerek dikkat eksikliği, hiperaktivite ve dürtüselliğe yol açan kronik ve çok etkenli bir hastalıktır. Asıl nedeni bilinmemekle birlikte dikkat eksikliği hiperaktivite bozukluğu hastalarında gözlemlenen düşük plasma omega-3 yağ asidi seviyeleri omega-3 yağ asidi takviyesini şeklinde yeni bir tedavi yaklaşımını ortaya çıkarmıştır. Yöntem: Omega-3 yağ asidi takviyesi ve dikkat eksikliği hiperaktivite bozukluğu tedavisi arasındaki ilişkiyi incelediğimiz literatür taraması 3 farklı veritabanı kullanılarak yapılmıştır. Dahil edilme kriterlerini karşılayan on dokuz çalışma detaylıca incelenmiştir. Bulgular: Daha fazla katılımcıyla ve daha uzun süreli yapılan çalışmalar omega-3 yağ asidi takviyesinin dikkat eksikliği hiperaktivite bozukluğunun tedavisinde yararlı etkilerini ortaya koymuştur. Aynı zamanda güncel tedavi yöntemlerine kıyasla daha ciddi yan etkiler gözlemlenmemiştir. Tartışma: Dikkat eksikliği hiperaktivite bozukluğunun omega-3 yağ asidi takviyesiyle tedavisi yaklaşımı sıklıkla incelenen bir konu olmasına ragmen konuya ilişkin kapsamlı bir literatur taramasının eksikliği görülmüştür. Bu literatür taramasında, ek ve daha kapsamlı klinik araştırmalara ihtiyaç duyulduğunu vurgulamakla beraber omega-3 yağ asidi takviyesinin dikkat eksikliği hiperaktivite bozukluğu tedavisinde faydalı olduğu sonucuna ulaşmış bulunmaktayız. .
Attention Deficit Hyperactivity Disorder and Omega-3 Fatty Acid Supplementation: A Systematic Review
Objective: Attention deficit hyperactivity disorder (ADHD) is a chronic multifactorial disorder mainly affecting school-aged children and resulting in inattention, hyperactivity and impulsivity symptoms. While exact underlying cause remains unknown, observations regarding the low plasma levels of omega-3 fatty acids in ADHD patients leads to a new treatment approach, omega-3 fatty acid supplementation. Method: Literature search is performed about the relation between omega-3 fatty acid supplementation and ADHD treatment by using 3 databases. Nineteen studies met the inclusion criteria and further analyzed. Results: Studies performed with higher number of participants and for longer trial period demonstrate beneficial effects of omega-3 fatty acids in ADHD treatment while no significant additional adverse effects are recorded compared to regular treatment options. Discussion: Omega-3 fatty acid supplementation approach in ADHD treatment is one of the highly investigated issues while there is a lack of comprehensive literature review regarding that issue. In this literature review, we conclude beneficial effects of omega-3 fatty acids in ADHD treatment while it is important to emphasize the need for additional and more comprehensive clinical trials about this issue.

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