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Yıl:1995; Cilt: 32; Sayı: 3>> Özet
Nöropsikiyatri Arşivi; 1995;32(3):111-116
Yeni Antiepileptikler ve Etki Mekanizmaları
R Bilgin
SSK Buca Hastanesi, Nöroloji Servisi
Yeni antiepileptik droglarm bir bölümü geçtiğimiz yıllar içinde geliştirilerek piyasaya sunulmuştur. Batı ülkelerinde halen kullanılmakta olan bu droglarm dışında, bazıları da geliştirilme sürecindedir. Geleneksel antiepileptik droglar ile birlikte kullanılan bu ilaçların, genellikle, önemli yan etkilerinin olmaması seçilme nedenlerindendir. Ayrıca; etkinlikleri, farmasötik özellikleri, farmakokinetik profilleriyle de aranılan ölçütlere uymaktadırlar.
On yılı aşkın bir süredir, önemli bir tıbbi tedavi seçeneğinin sunulamadığı bu alanda, yeni antiepileptikler sınırlı bir iyimserlikle karşılanmaktadır
New Antiepileptics and Their Mechanism of Action
Some of the new antiepileptic drugs which were be­ing used in Western countries were offered to our clinical use and on the market in the last 5 [year]s, There are still new antiepileptic drugs in the la­boratory and clinical trial phases. These new antiepileptics are mostly used in com­bination with the old traditional antiepileptics. The reason that they are preferred is that they have fewer side effects and their clinical effects, pharmacokinetic profiles and pharmaceutic prop­erties are very favorable.
In a field where there isn't any other treatment al­ternative, we consider the new antiepileptics with a limited optimism.

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