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Yıl:2018; Cilt: 55; Sayı: 3>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2018;55(3):233-237
Migrende Diyet Kısıtlamasının Etkinliği
AÖ Özön, Ö Karadaş, A Özge
Liv Hospital, İstanbul
Amaç: Migren tipi baş ağrısı çok sık karşılaşılan bir baş ağrısı olup hala patogenezi tam olarak anlaşılmış değildir. Migreni tetikleyen faktörler migren hastalarında farklılık göstermekle birlikte, bazı yiyecek alımının kısmi önemi mevcuttur. Bu çalışmada migreni tetikleyici bazı gıdaların alımının kısıtlanmasının, migren ataklarının önlenmesi üzerindeki etkinliği araştırıldı. Yöntem: Çalışmaya Uluslararası Baş ağrısı sınıflamasına göre aurasız migren tanısı konulan hastalar alındı. Migren atağının belirli gıdaların alımından sonra başladığını belirten 50 migren hastası değerlendirildi. Hastalar randomize olarak 2 gruba ayrıldı. Hem grup 1 (n=25) hem de grup 2 (n=25) hastaları için belirlenen tetikleyici gıdalar o hastanın diyetinden çıkarıldı. Diyet kısıtlamasına başlamadan önce ve diyet uygulama sonrası 2. ayda, bir ay içerisindeki atak sıklığı, atak süresi ve Görsel Analog Skala ile ağrı şiddetleri kaydedildi. İkinci aydan sonra grup 1 hastalarındaki diyet kısıtlaması kaldırıldı ve grup 2 için diyet kısıtlamasına devam edilerek 4. ayda her iki grupta, bir ay içerisindeki atak sıklığı, atak süresi ve Görsel Analog Skala ile ağrı şiddetleri saptandı. Bulgular: Çalışmada 9’u erkek 41’i kadın olmak üzere toplam 50 hasta değerlendirildi. Her iki grupta hastalara diyet uygulama sonrası 2. ayda, bir ay içerisindeki atak sıklığı, atak süresi ve ağrı şiddetleri, diyet uygulama öncesine göre istatisiksel olarak anlamlı derecede daha düşük olarak saptandı. [grup 1 p değerleri sırasıyla (p=0,011, p=0,041, p=0,003), grup 2 p değerleri sırasıyla (p=0,015, p=0,037, p=0,003)]. Dördüncü ayda yapılan değerlendirmede sadece grup 2’de bu anlamlılığın devam ettiği görüldü. Sonuç: Çalışma sonuçları migren hastalarında, migren ataklarını tetikleyici gıdaların olduğu tespit edildiğinde, bu gıdaların alımının kısıtlanması, migren ataklarının azaltılmasında etkin ve güvenilir bir tedavi yöntemi olabileceğini ortaya koymaktadır.
Efficacy of Diet Restriction on Migraines
Introduction: Migraine is a common type of headache, but its pathogenesis is still not fully understood. Triggering factors may vary in migraine patients with a particular importance of certain food intake. In this study, the efficacy of limiting certain migraine- triggering foods in the prevention of migraine attacks was investigated. Methods: Patients diagnosed with migraine without aura according to the International Classification of Headaches were enrolled. Fifty migraine patients stating that migraine attack started after the intake of certain foods were evaluated. The patients were randomly divided into 2 groups. The migraine-triggering foods identified by the patients were excluded from the diet in both groups 1 (n=25) and 2 (n=25). Monthly attack frequency, attack duration, and attack severity (using the visual analogue scale) were recorded before starting the diet restriction and 2 months after the diet restriction. Diet restriction was relaxed in group 1 after the second month and continued in group 2. In the fourth month, the monthly attack frequency, attack duration, and attack severity (using the visual analogue scale) were determined in both groups. Results: A total of 50 patients comprising 9 males and 41 females were evaluated in this study. In both the groups, in the second month after diet implementation, monthly attack frequency, attack duration, and attack severity were found to have decreased to a statistically significant extent compared to those in the period before diet implementation [group 1 (p=0.011, p=0.041, and p=0.003, respectively) and group 2 (p=0.015, p=0.037, and p=0.003, respectively)]. In the evaluation in the fourth month, it was observed that this significant decrease was maintained only in group 2. Conclusion: The results of the study reveal that if migraine-triggering foods are identified by migraine patients, restricting their intake can be an effective and reliable method to reduce migraine attacks.

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