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Yıl:2018; Cilt: 55; Sayı: 3>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2018;55(3):220-224
Migren'de Kraniyal Otonomik Bulgular ve Küme Başağrısında Migrenöz Özellikler
D Uluduz, S Ayta, A Özge, OÖ Yalın, Turkish Headache Database Study Group, GÖi Temel, B Taşdelen
İstanbul Üniversitesi, İstanbul
Amaç: Migren hastalarında bulunan kraniyal otonomik bulgular ve küme başağrısında bulunan migrenöz özellikler ile ilgili bilgilerimiz kısıtlıdır. Yöntem: Çalışmaya 2955 migren ve 93 küme başağrısı tanılı hasta dahil edildi. Migren hastalarında pitoz, göz yaşarması, rinore, fasyal ödem, konjunktival injeksiyon, ve pupil değişikliklerini içeren otonomik semptomların varlığı incelendi. Ayrıca küme başağrısı tanılı olgularda bulantı, kusma, fotofobi ve fonofobi gibi migrenöz bulguların varlığı kaydedildi. Bulgular: Otonomik semptom bulunan ve bulunmayan migren hastalarında anlamlı farklılıklar saptandı. Unilateral başağrısı, periokuler lokalizasyon, açlıkla tetiklenme, ve karın ağrısı hikayesi otonom semptomların bulunma riskini anlamlı olarak artırdığı gözlendi. Otonom semptomların eşlik ettiği migren tanısında en yüksek duyarlılık (%94.38) ve özgünlüğe (%99.89) sahip bulgular lakrimasyon, fasiyal ödem ve konjunktival injeksiyon idi. Sonuç: Migren ve küme başağrısı klinik ve patofizyolojilik olarak iki farklı antite olarak kabul edilmektedirler. Otonomik semptomların araştırılması tanıda önemlidir ve gerçek prevalanslarının saptanabilmesi için başağrısı uzmanlarının bu birlikteliği günlük pratikte sorgulamaları gerekmektedir. özellikle lakrimasyon, konjunktival injeksiyon ve fasiyal ödem migren hastaları tarafından sık bildrilen otonom semptomlardır.
Cranial Autonomic Features in Migraine and Migrainous Features in Cluster Headache
Introduction: Limited data about the importance of cranial autonomic features of migraines and migrainous features of cluster headaches are available. Methods: We enrolled 2955 patients with migraine and 93 patients with cluster headache. We explored the autonomic features, including ptosis, lacrimation, rhinorrhea, facial swelling, conjunctival injection, and pupil changes. The presence of migrainous features, such as nausea, vomiting, photophobia, and phonophobia, in cluster headache patients were noted. Results: Migraine patients with underlying autonomic symptoms (MwuAS) and those without differed significantly. Unilaterality, periocular localization of headaches provoked by starvation, and history of abdominal pain significantly increased the risk of MwuAS. The parameters with the highest sensitivity (94.38%) and specificity (99.89%) for the diagnosis of MwuAS were lacrimation, facial swelling, and conjunctival injection. Conclusion: Migraine and cluster headache are considered two different entities with different pathophysiologies. The assessment of autonomic symptoms is essential, and specialists must consider such an overlap in clinical practice in order to obtain accurate prevalence rates. In particular, lacrimation, conjunctival injection, and facial swelling are widely experienced by migraineurs.

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