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Yıl:2018; Cilt: 55; Sayı: 2>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2018;55(2):146-151
Epizodik ve Kronik Migrende Blink Refleks
B Polat, F Aysal, M Öztürk, B Mutluay, Y Altunkaynak, NH Yılmaz, S Baybaş
İstanbul Medipol Üniversitesi, İstanbul
Amaç: Trigeminovasküler sistemin aktivasyonu ve beyin sapı trigeminal nukleuslarının sensitizasyonu migren fizyopatolojisinde önemli bir rol oynamaktadır. Bu çalışmanın amacı epizodik ve kronik migrenli hastalarda, göz kırpma refleksi (GKR) ve GKR toparlanma cevaplarını araştırmaktır. Yöntem: Çalışmaya 28 kronik migrenli, 32 epizodik aurasız (ağrısız dönemde) migrenli iki hasta grubu ve 30 sağlıklı kontrol alındı. Portabl EMG cihazında, GKR için özel hazırlanmış program kullanıldı. Hastalara (ağrısız dönemde) ve kontrollere ‘standart yöntem - ikili uyarı’ tekniği ile 200 ms, 500 ms, 1000 ms, 2000 ms ve 5000 ms inter stimulus intervallerinde (ISI) GKR ve GKR toparlanması çalışıldı. Bulgular: Hem kronik hem de aurasız migren grubunda, kontrol grubuna göre, 200 ms ISI’da her iki tarafta (sağ ve sol) da GKR toparlanması anlamlı olarak (p
Blink Reflex in Episodic and Chronic Migraine
Introduction: Activation of the trigeminovascular system and sensitization of brainstem trigeminal nuclei play a significant role in the physiopathology of migraine. Our aim was to investigate blink reflex (BR) and its recovery in episodic and chronic migraine patients. Methods: Twenty-eight chronic migraine patients, thirty-two episodic migraine without aura patients and thirty healthy controls were included in the study. The study was performed using a portable electromyography device with a software specifically prepared for BR. Blink reflex assessments were performed in patients during the painfree period and in healthy controls using the ‘standard method - double stimulation’ technique in 200 ms, 500 ms, 1000 ms, 2000 ms, and 5000 ms intervals. Results: Blink reflex recovery was significantly increased in both patient groups as compared to the control group in 200 ms interstimulus interval (ISI) on both sides (p

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