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Yıl:2018; Cilt: 55; Sayı: 1>> Özet
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Nöropsikiyatri Arşivi; 2018;55(1):29-35
Yineleyen-Düzelen Multipl Skleroz Hastalarında Yaşam Kalitesi Sağlığı ile İlgili Psikososyal ve Tıbbi Belirleyiciler
IR Boogar, S Talepasand, M Jabarı
Semnan Üniversitesi, İran
Giriş: Yineleyen-düzelen multipl skleroz, yaşam kalitesini olumsuz yönde etkileyen zayıflatıcı bir nörolojik hastalıktır. Bu çalışmanın amacı, yineleyen-düzelen multipl skleroz hastalığının sağlıkla ilişkili yaşam kalitesinin psikolojik, hastalıkla ilişkili, sosyoekonomik ve demografik belirleyicileri üzerindeki rolünü araştırmaktır. Yöntem: Bu kesitsel ve tanımlayıcı çalışmada, Mart 2014’ten Temmuz 2014’e kadar Tahran’daki İran Multipl Skleroz Derneğine katılan, yineleyen-düzelen multipl sklerozlu 193 hasta, uyum örnekleme yöntemi ile seçildi; bu hastalar, Multipl Skleroz Yaşam Kalitesi Anketini, Depresyon Kaygı ve Stres Ölçeklerini ve Sosyo-demografik Anketi doldurdular.. Ardından PASW-18’in veri analizi için basamaklı yöntemle hiyerarşik çoklu regresyon analizi yapılmıştır. Bulgular: Elde edilen bulgulara göre, model 1’de, düşük sosyoekonomik statü için negatif katsayı (beta=-0,30, p0.05). Sonuç: Olumsuz sosyoekonomik statü, etkili tedavi geçmişi yokluğu, yüksek depresyon ve multipl skleroz belirtileri ve semptom şiddeti, yineleyen-düzelen multipl skleroz hastalarında sağlıkla ilişkili yaşam kalitesinin azalmasını önemli ölçüde öngörmektedir. Bu nedenle sonuç olarak, yineleyen-düzelen multipl sklerozda yaşam kalitesinin iyileştirilmesine yönelik tedavi ve rehabilitasyon çalışmalarında, bu faktörleri göz önüne alan özelleştirilmiş müdahalenin değerinin önemi ortaya çıkmaktadır.
Psychosocial and Medical Determinants of Health-related Quality of Life in Patients with Relapsing-Remitting Multiple Sclerosis
Introduction: Relapsing-remitting multiple sclerosis is a debilitating neurological disease accompanied with adverse consequences for quality of life. The purpose of this study was to investigate the role of relapsing-remitting multiple sclerosis on psychological, disease-related, socioeconomic, and demographic determinants of health-related quality of life of patients. Methods: In this cross-sectional descriptive study, 193 patients with relapsing-remitting multiple sclerosis were selected by compliance sampling method among the patients who attended the Iranian Multiple Sclerosis Association in Tehran from March 2014 to July 2014; and they completed the Multiple Sclerosis Quality of Life Questionnaire, the Depression Anxiety and Stress Scales, and the Socio-demographical Questionnaire. Then, a hierarchical multiple regression analysis with the stepwise method is used for data analysis by the PASW-18. Results: According to the findings, in model 1, low socioeconomic status (SES) had a negative coefficient (beta=-0.30, p0.05). Conclusion: Unfavorable SES, lack of effective treatment history, higher depression, and signs and symptoms severity of multiple sclerosis significantly predict decreased health-related quality of life in patients with relapsing-remitting multiple sclerosis. Thus, it is consequential to emphasize the value of tailored intervention for attending to these factors in the treatment and rehabilitation agendas for improvement of health-related quality of life in relapsing-remitting multiple sclerosis.

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