Dergi Ara >>
Yıl:2018; Cilt: 29; Sayı: 3>> Özet
TAM METİN
Türk Psikiyatri Dergisi; 2018;29(3):162-170
Ötimik Bipolar Tip II Bozukluğu olan Hastalarda Psikososyal İşlevsellik Düzeyleri ve İlişkili Klinik ve Bilişsel Etmenler
RS İlhan, H Demirel, VŞ Cankorur
Nafiz Körez Sincan Devlet Hastanesi, Ankara
Giriş: Bu çalışmanın amacı bipolar tip II bozukluğu (BB-II) olan hastaların ötimik dönemdeki psikososyal işlevsellik düzeylerinin belirlenmesi ve psikososyal işlevsellik düzeyi ile klinik ve bilişsel özellikler arasındaki ilişkinin araştırılmasıdır. Bu araştırmada ötimik BB-II hastalarının sağlıklı kontrollere göre daha düşük psikososyal işlevsellik düzeylerine sahip olduğu ve psikososyal işlevsellik düzeyi ile klinik belirtilerin ve bilişsel işlev bozukluğunun ilişkili olduğu hipotezleri test edilmiştir. Yöntem: Çalışmaya DSM–IV için Yapılandırılmış Klinik Görüşme ile BB-II tanısı konmuş 33 hasta ile 35 sağlıklı kontrol çalışmaya dahil edilmiştir. Psikososyal işlevsellik düzeyi Kısa İşlevsellik Derecelendirme Ölçeği (KİDÖ) ile klinik belirtiler Hamilton Depresyon (HAM-D), Young Mani, Hamilton Anksiyete Derecelendirme Ölçeği (HAM-A) ile değerlendirilmiştir. Nörolobilişsel test bataryası WAIS-R genel bilgi alt testi, Wisconsin Kart Eşleme Testi’nin (WKET) perseveratif hata sayısı, perseveratif olmayan hata sayısı ve kategori tamamlama alt testleri, İz Sürme Testi -B (İST-B) Stroop testi TBAG, İz Sürme Testi-A (İST-A), İşitsel Üçlü Sessiz Harf Sıralama Testi (İÜSHST) ve Wechsler Bellek Ölçeği geliştirilmiş formu (WBÖ) testlerinden oluşturulmuştur. Bulgular: Psikososyal işlevselliğin değerlendirildiği KİDÖ ile klinik belirtilerin değerlendirildiği HAM-D ve HAM-A puanları iki grup arasında anlamlı farklı bulunmuştur. Bilişsel işlevlerin değerlendiridiği WKET tamamlanan kategori, İST-B, Stroop, İST-A, İÜSHST ve WBÖ puanları da iki grup arasında anlamlı farklılık göstermektedir. Bipolar II grubunda KİDÖ puanları İÜSHST puanları ile ilişkili bulunmuştur. Sonuç: BB-II bozukluğu olan hastalar ötimik dönemlerinde sağlıklı kontrollere göre düşük psikososyal işlevsellik düzeyi, depresyon ve anksiyete belirtileri ve bilişsel işlevlerde bozukluk göstermektedir. Bu çalışma bulgularına göre ötimik BB-II hastalarının psikososyal işlevsellik düzeyleri işlem belleği kusuru ile diğer değişkenlerden bağımsız olarak ilişkidir
Psychosocial Functioning in Euthymic Patients with Bipolar Disorder Type–II and Associated Clinical and Cognitive Factors
Objective: The aim of this study was to investigate psychosocial functioning of euthymic Bipolar Disorder Type-II (BD-II) patients and the association between psychosocial functioning with cognitive functions and subclinical symptoms. The hypothesis was BD-II patients would have low level of psychosocial functioning comparing to healthy subjects and psychosocial functioning would be associated independently with cognitive dysfunction and subclinical symptoms. Method: Thirthy-three subjects who met criteria for BD-II according to Structured Clinical Interview for DSM-IV and thirty-five healthy subjects were included. Clinical symptoms were assessed by Hamilton Depression Rating Scale (HDRS), Young Mania Rating Scale (YMRS); Hamilton Anxiety Rating Scale (HARS); psychosocial functioning was assessed by Functioning Assessment Short Test (FAST). Neurocognitive assessment battery was consisted of WAIS-R general information subtest; Wisconsin Card Sorting Test (WCST) perseverative errors, nonperseverative errors and category completed subtests; Trail Making Test-B (TMT-B); Stroop TBAG form; Trail Making Test-A(TMT-A) Auditory Consonant Trigrams (ACT) ACT; Wechsler Memory Scale Revised (WMS-R). Results: Clinical symptoms assessed by HDRS, HARS scores; psychosocial functioning scores assessed by FAST; neurocognitive functions assessed by WCST category completed and, TMT-B, Stroop test, TMT-A, ACT, and WMS-R scores were significantly different between the two groups. FAST scores were associated with ACT scores in BB-II group. Conclusion: BB-II patients had cognitive dysfunctions and low level of psychosocial functioning even in their euthymic states. Working memory dysfunction was independently associated with psychosocial functioning of euthymic BB-II patients.

http://www.simplehandbaga.com/hermes-constance-bag-23cm-togo-leather-black-gold.html http://www.simplehandbaga.com/hermes-garden-party-handbag-small-31cm-red.html http://www.simplehandbaga.com/hermes-birkin-35cm-cattle-skin-vein-handbags-orange-golden.html http://www.simplehandbaga.com/hermes-jige-clutch-29cm-croco-white-grey.html http://www.simplehandbaga.com/hermes-kelly-32cm-ostrich-vein-6108-black-golden.html http://www.simplehandbaga.com/hermes-jige-clutch-29cm-croco-dark-red.html http://www.simplehandbaga.com/hermes-herbag-31cm-green-canvas-bag.html http://www.simplehandbaga.com/hermes-epsom-leather-wallet-camel-silver.html http://www.simplehandbaga.com/hermes-calf-leather-men-h-belt-138-silver-blue.html http://www.simplehandbaga.com/hermes-so-kelly-28cm-togo-leather-shoulder-bag-green-silver.html http://www.simplehandbaga.com/hermes-kelly-32cm-togo-leather-6108-electric-blue-silver.html http://www.simplehandbaga.com/hermes-epsom-leather-jige-clutch-29cm-orange.html http://www.simplehandbaga.com/hermes-birkin-30cm-togo-leather-handbag-blue-gold.html http://www.simplehandbaga.com/hermes-medor-clutch-29cm-croco-burgundy.html http://www.simplehandbaga.com/hermes-bolide-31cm-togo-leather-pink-bag.html http://www.simplehandbaga.com/hermes-birkin-35cm-handbag-crocodile-leather-green-gold.html http://www.simplehandbaga.com/hermes-constance-23cm-croco-leather-black.html http://www.simplehandbaga.com/hermes-lindy-30cm-handbag-pink-silver.html http://www.simplehandbaga.com/hermes-garden-party-handbag-small-31cm-elephant-grey.html http://www.simplehandbaga.com/hermes-birkin-35cm-togo-leather-handbags-dark-blue-golden.html http://www.simplehandbaga.com/hermes-jige-wallet-togo-leather-black.html http://www.simplehandbaga.com/hermes-dogon-wallet-togo-leather-h001-brown.html http://www.simplehandbaga.com/hermes-kelly-cut-31cm-epsom-leather-clutch-orange.html http://www.simplehandbaga.com/hermes-jige-wallet-togo-leather-electric-blue.html http://www.simplehandbaga.com/hermes-jige-wallet-togo-leather-pink.html http://www.simplehandbaga.com/hermes-h-wallet-royal-blue-silver.html http://www.simplehandbaga.com/hermes-birkin-30cm-togo-leather-handbags-black-gold.html http://www.simplehandbaga.com/hermes-kelly-cut-31cm-epsom-leather-clutch-electric-blue.html http://www.simplehandbaga.com/hermes-lindy-30cm-handbag-blue-silver.html http://www.simplehandbaga.com/hermes-dogon-wallet-togo-leather-h001-burgundy.html http://www.simplehandbaga.com/hermes-medor-clutch-29cm-croco-grey.html http://www.simplehandbaga.com/hermes-constance-bag-23cm-epsom-leather-grey-gold.html http://www.simplehandbaga.com/hermes-kelly-cut-31cm-epsom-leather-clutch-elephant-grey.html http://www.simplehandbaga.com/hermes-calf-leather-wallet-h005-red.html http://www.simplehandbaga.com/hermes-lindy-30cm-handbag-camel-gold.html http://www.simplehandbaga.com/hermes-kelly-wallet-togo-leather-black.html http://www.simplehandbaga.com/hermes-epsom-leather-jige-clutch-29cm-orange.html http://www.simplehandbaga.com/hermes-mini-evelyne-tpm-bag-pink.html http://www.simplehandbaga.com/hermes-herbag-31cm-burgundy-canvas-bag.html http://www.simplehandbaga.com/hermes-mini-kelly-22cm-epsom-leather-yellow-silver-with-chain-strap.html http://www.simplehandbaga.com/hermes-constance-bag-23cm-togo-leather-blue-silver.html http://www.simplehandbaga.com/hermes-30cm-birkin-bag-togo-leather-with-strap-light-pink-gold.html http://www.simplehandbaga.com/hermes-jige-wallet-togo-leather-blue.html http://www.simplehandbaga.com/hermes-birkin-35cm-togo-leather-handbags-rose-silver.html http://www.simplehandbaga.com/hermes-garden-party-handbag-small-31cm-brown.html http://www.simplehandbaga.com/hermes-jige-clutch-29cm-croco-green.html http://www.simplehandbaga.com/hermes-epsom-leather-jige-clutch-29cm-brown.html http://www.simplehandbaga.com/hermes-garden-party-handbag-small-31cm-blue.html http://www.simplehandbaga.com/hermes-birkin-35cm-cattle-skin-vein-handbags-blue-gold.html http://www.simplehandbaga.com/hermes-birkin-25cm-handbag-6068-orange-silver.html http://www.simplehandbaga.com/hermes-garden-party-handbag-large-36cm-black.html http://www.simplehandbaga.com/hermes-birkin-35cm-togo-leather-handbags-red-silver.html http://www.simplehandbaga.com/hermes-constance-bag-23cm-epsom-leather-pink-silver.html http://www.simplehandbaga.com/hermes-kelly-cut-31cm-epsom-leather-clutch-pink.html http://www.simplehandbaga.com/hermes-calf-leather-wallet-h005-in-orange.html http://www.simplehandbaga.com/hermes-picotin-lock-togo-leather-red.html http://www.simplehandbaga.com/hermes-mini-kelly-22cm-epsom-leather-green-silver-with-chain-strap.html http://www.simplehandbaga.com/hermes-birkin-25cm-handbag-6068-orange-silver.html http://www.simplehandbaga.com/hermes-birkin-35cm-togo-leather-handbag-yellow-gold.html http://www.simplehandbaga.com/hermes-birkin-35cm-cattle-skin-vein-handbags-orange-golden.html http://www.simplehandbaga.com/hermes-constance-bag-23cm-togo-leather-camel-gold.html http://www.simplehandbaga.com/hermes-calf-leather-men-h-belt-138-gold-light-coffee.html http://www.simplehandbaga.com/hermes-kelly-28cm-bag-togo-leather-blue-gold.html http://www.simplehandbaga.com/hermes-garden-party-handbag-small-31cm-pink.html http://www.simplehandbaga.com/hermes-garden-party-handbag-large-36cm-red.html http://www.simplehandbaga.com/hermes-birkin-30cm-togo-leather-handbag-burgundy-gold.html http://www.simplehandbaga.com/hermes-mini-evelyne-tpm-bag-dark-blue.html http://www.simplehandbaga.com/hermes-birkin-35cm-cattle-skin-vein-handbags-light-coffee-silver.html http://www.simplehandbaga.com/hermes-so-kelly-28cm-togo-leather-shoulder-bag-hot-pink-silver.html http://www.simplehandbaga.com/hermes-birkin-30cm-togo-leather-handbags-black-gold.html http://www.simplehandbaga.com/hermes-medor-clutch-29cm-croco-white.html http://www.simplehandbaga.com/hermes-garden-party-36cm-leather-handbag-black-hot-pink.html http://www.simplehandbaga.com/hermes-birkin-35cm-handbag-crocodile-leather-brown-gold.html http://www.simplehandbaga.com/hermes-constance-wallet-togo-leather-rose.html http://www.simplehandbaga.com/hermes-bi-fold-wallet-h006-black.html http://www.simplehandbaga.com/hermes-constance-bag-23cm-epsom-leather-red-gold.html http://www.simplehandbaga.com/hermes-birkin-35cm-togo-leather-handbags-black-silver.html http://www.simplehandbaga.com/hermes-mini-evelyne-tpm-bag-blue.html http://www.simplehandbaga.com/hermes-calf-leather-men-h-belt-138-silver-blue.html http://www.simplehandbaga.com/hermes-epsom-leather-jige-clutch-29cm-black.html http://www.simplehandbaga.com/hermes-epsom-leather-jige-clutch-29cm-brown.html http://www.simplehandbaga.com/hermes-bolide-31cm-togo-leather-orange-bag.html http://www.simplehandbaga.com/hermes-calf-leather-wallet-h005-h-red.html http://www.simplehandbaga.com/hermes-medor-clutch-29cm-croco-burgundy.html http://www.simplehandbaga.com/hermes-birkin-35cm-crocodile-leather-handbag-grey-white-gold.html http://www.simplehandbaga.com/hermes-lindy-30cm-handbag-red-gold.html http://www.simplehandbaga.com/hermes-birkin-35cm-cattle-skin-vein-handbags-dark-khaki-silver.html http://www.simplehandbaga.com/hermes-garden-party-36cm-canvas-handbag-yellow.html http://www.simplehandbaga.com/hermes-calf-leather-8616-handbag-cherry-pink.html http://www.simplehandbaga.com/hermes-kelly-cut-31cm-epsom-leather-clutch-orange.html http://www.simplehandbaga.com/hermes-lindy-30cm-handbag-orange-silver.html http://www.simplehandbaga.com/hermes-dogon-wallet-togo-leather-h001-blue.html http://www.simplehandbaga.com/hermes-birkin-35cm-handbag-crocodile-leather-green-gold.html http://www.simplehandbaga.com/hermes-mini-kelly-22cm-epsom-leather-yellow-silver-with-chain-strap.html http://www.simplehandbaga.com/hermes-mini-evelyne-tpm-bag-camel.html http://www.simplehandbaga.com/hermes-constance-bag-23cm-togo-leather-black-gold.html http://www.simplehandbaga.com/hermes-mini-evelyne-tpm-bag-green.html http://www.simplehandbaga.com/hermes-dogon-wallet-togo-leather-h001-green.html http://www.simplehandbaga.com/hermes-birkin-35cm-cattle-skin-vein-handbags-blue-gold.html http://www.simplehandbaga.com/hermes-constance-23cm-togo-leather-orange-silver.html