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Yıl:1997; Cilt: 34; Sayı: 3>> Özet
Nöropsikiyatri Arşivi; 1997;34(3):141-143
Bir Esansiyel Tremor Olgusunun Botulinum Toksini Enjeksiyonu İle Tedavisi
YG Parman, AE Öge, J Yazıcı, A Boyacıyan
İstanbul Üniversitesi İstanbul Tıp Fakültesi Nöroloji Anabilim Dalı\r\n
Esansiyel tremor (ET) en sık görülen aksiyon tremorudur. Prevalansı 40 yaşın üzerinde % 0.3-5 arasında değişir. Ciddi fiziksel, psikolojik handikap oluşturabilir. Son yıllarda ilaçla tedavinin yetersiz kaldığı olgularda botulinum toksini (BT) enjeksiyonu bazı yazarlarca önerilmektedir. BT intramüsküler olarak uygulanan, periferik sinir uçlarında asetilkolin salınımını bloke ederek geçici kas zaafı yapan bir nörotoksindir. Günümüzde artık fokal distoni tedavisinde önemli bir yeri vardır. Esansiyel el tremorunda tremoru ortaya çıkaran önkol agonist ve antagonist kasları iğne EMG'si ile saptanarak enjekte edilmektedir. Baş ve el tremoru olan, medikal tedaviden yarar görmemesi üzerine BT uygulanan ve bu yaklaşımdan yarar gören bir olgu sunulacaktır.
Treatment of Essential Tremor With Botulinum Toxin
Essential tremor (ET) is the most common action tremor, with a prevalence between 0.3 and 5 % over 40 [year]s of age. It is a "benign" disease but can produce serious physical and psychological handicap. ET can be sporadic. Botulinum toxin (BT) which is a well -established treatment for focal dystonias has recently been used in ET. In this paper a 69 - [year] - old woman who did not respond well to drug treatment, improved after BT mjestion is presented.

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