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Yıl:1997; Cilt: 34; Sayı: 4>> Özet
Nöropsikiyatri Arşivi; 1997;34(4):186-191
Cinsel İşlev Bozukluklarında İlaç Tedavileri
HE Özmen
Bakırköy Ruh ve Sinir Hastalıkları Hastanesi
Çeşitli nedenlerle cinsel tedavilerin uygulana­madığı durumlarda iyi seçilmiş ilaç tedavisi-nin danışanların en azından belli bir grubun­da yararlı olduğuna ilişkin bilgi ve deneyim birikimi son yıllarda yoğunlaşmıştır. Er&en boşalmada serotoninerjik etkili antidepres-sanlar yan etkilerinin azlığı nedeniyle öneril­mektedir.
Sertleşme bozukluklarında dopaminerjik ilaç­lar, yohimbin, testesteron, LRHR, prostaglan­din E, trazodon, ve SSRI'lann yararlı olabile­ceğine ilişkin çok sayıda araştırma vardır. Sertleşme bozuklarında kullanılan ilaçlar cin­sel istek azlığı ile başvuran danışanlarda da kullanılabilir. Cinsel yanıt fazlarının karmaşık mekanizmaları ile ilgili bilgilerin artması ve daha özgün ilaçların geliştirilmesiyle, ilaç te­davisinin yakın gelecekte cinsel işlev bozuk­luklarında önde gelen seçeneklerden biri ol­ması beklenmektedir. Bu gün için olası yan etkilerin göz önüne alınarak, ilaç kullanımı­nın cinsel terapilerin uygulanamadığı durum­larla sınırlı kalması; uygun danışan grubunda uygun ilacın seçimine özen gösterilmesi; cin­sel bilgilendirme ve rehberliğin ihmal edilme­mesi gerekmektedir.
Pharmacotherapy in Sexual Dysfunctions
Pharmacological intervention in sexual dysfunctions is considered to be useful in a group of patients for whom psychotherapeutic approach is not applicable. Serotoninergic an­tidepressants are beneficial in premature eja­culation, considering their efficiency and sa­fety. Numerous trials suggest that dopami­nergic agents, yohimbine, testosterone, HLHRH, prostaglandin E, trazodone and SSRI's may be useful in erectile dysfunction. The same group of drugs could also be used for impaired sexual desire. Future investigati­ons about the neurophysiology of human se­xual responsivity would facilitate the develop­ment of more spesific, potent and safe drugs, causing pharmacotherapy to be a prominent alternative in this field. Currently, drug treatment for sexual dysfunctions should be limi­ted and appropriately planned.

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