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Yıl:1998; Cilt: 35; Sayı: 3-4>> Özet
Nöropsikiyatri Arşivi; 1998;35(3-4):156-161
Dikkat eksikliği, aşırı hareketlilik bozukluğunun (DEHB) yeni tedavi seçenekleri: Alfa 2 adrenerjik agonistleri klonidin ve guanfasin
V Topçuoğlu, AR Arman, MY Yazgan
Marmara Üniversitesi Psikiyatri Anabilim Dalı
Bu yazıda Dikkat Eksikliği Aşın Hareketlilik Bozukluğu tedavisinde ruhsal uyarıcı ilaçlara seçenek olabilecek alfa 2 agonisti maddeler, kloni-din ve guanfasin ele alınmıştır. Ruhsal uyarıcıların belirtileri azaltmada %70 etkili olduğu vurgulan­makla birlikte, özellikle yan etkileri ve eşlik eden bozukluklar nedeniyle başka tedavi seçenekleri gündeme gelmektedir. Asıl kullanım endikasyonu hipertansiyon olan klonidin ve guanfasinin DEAHB belirtileri üzerine etkileri ve kullanım örnekleri ile birlikte farmakolojik yapıları yazının ana hatlarını oluşturmaktadır.
Alpha 2 Adrenergic Agonists Clonidine And Guanfacine: Alternative Choices In The Treatment Of Attention Deficit Hyperactivity Disorder
Alpha 2 agonist agents, clonidine and guanfacine can be alternative choices to psychostimulants in the treatment of Attention Deficit Hyperactivity Disorder. Althoughpsychostimulants are known to be effective in controlling ADHD symptoms in 70% of cases, side effects and presence of comorbidity brings out the administration of other possibilities such as alpha 2 agonists. Effects on behavior, dosages, and pharmacologic structures of cloni­dine and guanfacine are outlined in this paper.

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