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Yıl:2005; Cilt: 15; Sayı: 3>> Özet
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Klinik Psikofarmakoloji Bülteni; 2005;15(3):134-137
Kemik iliği nakli yapılan DiGeorge anomalisi olan bir çocukta şiddetli DEHB’nun metilfenidatla tedavisi
O Sabuncuoğlu, F Karademir, M Berkem
Marmara University Department of Child and Adolescent Psychiatry
Çocuk yaş grubunda gerçekleştirilen kemik iliği nakilleri artmakta olduğu için psikofarmakolojik girişimlerle ilgili bilgileri de geliştirme gereksinimi vardır. Bu konuya klinik bir katkı yapmak için timus yokluğunu da içeren doğumsal bağışıklık yetmezliği sendromu nedeniyle kemik iliği nakli yapılan bir olguyu bildiriyoruz. Olgunun çocuk psikiyatrisine getiriliş nedeni aşırı hareketlilik ve zeka geriliğiydi. Gerekli tıbbi önlemler alındıktan sonra metilfenidat başlandı ve bir yıldan uzun süre devam edildi. Tedaviyle, dikkat eksikliği hiperaktivite bozukluğu (DEHB) belirtilerinde belirgin azalma ve eğitim ortamına daha iyi uyum elde edildi. Hastanın duyarlı bağışıklık sistemini etkileyen hiçbir yan etki gözlemlenmedi.(
Methylphenidate Treatment for Severe ADHD in a Bone Marrow Transplant Child with DiGeorge’s Anomaly
As the number of bone marrow transplantations (BMT) performed in the pediatric age group is on the rise, there is a growing need to expand our knowledge of psychopharmacological interventions in this special situation. We report a case who had undergone BMT for congenital immunodeficiency syndrome involving thymus aplasia. He was referred to the child psychiatry department with severe hyperactivity and mental retardation. Taking the necessary medical precautions, methylphenidate was started and continued for over a [year]. Marked improvement in the symptoms of attention deficit hyperactivity disorder (ADHD) and better adaptation to his educational setting were achieved. No adverse event occurred with regard to his vulnerable immune system

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