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Yıl:2002; Cilt: 3; Sayı: 4>> Özet
Anadolu Psikiyatri Dergisi; 2002;3(4):232-239
Fibromyalji sendromunun psikiyatrik bozukluklarla ilişkisi
Ş Tot, F Toros
Mersin Üniversitesi Tıp Fakültesi Psikiyatri Anabilim Dalı, MERSİN
Fibromyalji, genellikle genç yaştaki kadınlarda görülen, yaygın ve kronik ağrı ile karakterize bir sendromdur. Diğer kronik ağrı
sendromları gibi, fibromyaljide de ruhsal bozukluk sıklığında artış vardır. Majör depresyon, somatizasyon, panik ve obsesif
kompulsif bozukluk fibromyalji sendromu olanlarda sağlıklı kontrol gruplarına göre daha sık görülen ruhsal bozukluklardır.
Bundan dolayı, fibromyaljinin sıklıkla maskeli depresyon veya somatizasyon bozukluğu olduğu ileri sürülmüştür. Fibromyaljili
çoğu hastada yüksek anksiyete ve stres düzeyi bulunur. Fibromyaljili hastalarda çocukluk çağında fiziksel ve cinsel taciz gibi
stres dolu yaşam olayları sıktır. Çocukluk çağındaki stres dolu yaşam olayları fibromyaljiye sebep olmaz, stresle baş edebilme
mekanizmalarını etkiler. Uyku, ağrı ve duygudurum değişikliklerinde serotonin eksikliğinin katkısı olabileceği bildirilmiştir. Fibromyalji
sendromunda antidepresan ilaçlar depresif semptomlar yanında uyku bozuklukları ve ağrı üzerine de etkilidir. Antidepresan
ilaçlar başlangıçta genellikle düşük doz önerilir ve yavaşça artırılır. Bu etkiler serotonin, dopamin ve noradrenalin geri
alımına bağlıdır.
The relation of fibromyalgia syndrome and psychiatric disorders
Fibromyalgia is a common syndrome that is characterized by chronic, widespread pain affecting young women most commonly.
As in many chronic pain syndromes, there is an increased prevalence of psychological diagnosis in fibromyalgia. Major
depression, somatization, panic and obsessive compulsive disorder are more common psychiatric disorders in fibromyalgia
patients than in healty controls. Thus, fibromyalgia was often considered to be a form of ‘masked’ depression or a somatization
disorder. Furthermore, many patients do report high level of stress and anxiety. There are several reports of stressful life event
during (e.g. physically sexually abuse) childhood in fibromyalgia patients. This current consensus is that these childhood
experiences do not cause fibromyalgia, but adversely affect coping mechanisms. It has reported that defiency of serotonine
may integrate the changes in sleep, pain and mood. Antidepressants are recommended starting at very lower dose and making
increments cautiously. In addition to depressive symptoms antidepressant drugs are effective on sleep disorders, pain. These
effects are according to serotonine, dopamine and noradrenaline reuptake.

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