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Yıl:2001; Cilt: 11; Sayı: 3>> Özet
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Klinik Psikofarmakoloji Bülteni; 2001;11(3):187-191
Atipik antipsikotiklerin neden olduğu agranulositoz: Olgu sunumu
C Kısa, ES Yalçın, E Göka
Ankara Numune Eğitim ve Araştırma Hastanesi 1. Psikiyatri Kliniği
Atipik antipsikotik olarak değerlendirilen klozapin, tedaviye dirençli şizofreni olgularında standart antipsikotik tedaviden daha etkilidir. Kullanımı sağlayan ve fatal seyredebilecek en önemli yan etkisi agranülositoza yol açmasıdır. Son yıllarda, klozapin gibi diğer yeni antipsikotiklerin de agranüositoza neden olduğuna yönelik birçok olgu sunumu vardı. Klozapin ya da klozapin ve ketiapin kullanımına bağlı ortaya çıkan agranülositoz olgusunu sunmaktaki amacımız; agranülositoz hakkında literatürü gözden geçirmek ve bu olgunun tedavi deneyimini paylaşmaktı.
Agranulocytosis induced with atypical antipsychotics: A case report
Clozapine which is an atypical antipsychotic is more effective than standard antipsychotics in treatment resistant schizophrenia cases. The most important and fatal side effect of clozapine is agranulocytosis which can limit its usage. In recent [year]s, there have been many published case reports about neutropenic side effects of other novel antipsychotics like clozapine. Our aim of presenting agranulocytosis case due to clozapine or clozapine and quetiapine usage is; to review the literature about agranulocytosis and share our treatment experience with cases.

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