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Yıl:1998; Cilt: 8; Sayı: 4>> Özet
Klinik Psikofarmakoloji Bülteni; 1998;8(4):249-250
Selektif serotonin geri alım inhibitörleri ve beklenmeyen yan etkiler
R Aşkın, H Herken
Selçuk Üniversitesi Tıp Fakültesi Psikiyatri Kliniği-KONYA
Selektif serotonin geri alım inhibitörlerinin depresyon tedavisinde kullanım kolay­lığı ve güvenilirliği açıktır. Fluoxetine ile görülen yan etkilerle diğer SSRI yan etkileri arasında bir ilişkisi olmakla birlikte, diğer ilaçların daha seçilmiş ve az sayıda hasta­da kullanılması ender yan etkilerin tanınma ihtimalini azaltmaktadır. Bu noktada sert-ralin ve paroksetin hakkındaki bilgiler flouksetine kıyasla kısıtlıdır. Bu çalışmada pa-roksetin ve sertralin kullanımına bağlı gelişen tortikollis, akatizi ve üriner retansiyon vakası literatür ışığında incelendi.

SSRI's and unusual side effects
Selective serotonin reuptake inhibitors(SSRI) has resulted in increased tolerability and safety of antidepressant therapy. The adverse effects associated with other SSRIs are similiar to those seen with fluoxetine, although the fact that the other drugs have been given to fewer patients increases the possibility that some rare adverse effects are not fully recognised. In this event the data of paroxetine and sertraline are too li­mited according to data of fluoxetine. In this article three cases developing with akat-hisia, urinary retention and torticollis due to using paroxetine and sertraline are dis­cussed under the light of the data.

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