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Yıl:1998; Cilt: 8; Sayı: 2>> Özet
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Klinik Psikofarmakoloji Bülteni; 1998;8(2):54-58
Depresif bozukluklarda hipotalamik-pitüiter-tiroid eksen
M Bilici
Karadeniz Teknik Üniversitesi, Trabzon
Psikiyatrik bozukluklarda yapılan nöroendokrin çalışmalar, sıklıkla Hipotalamik-Pitüiter-Adrenal Eksen (HPA) ve Hipotalamik-Pitüiter-Tiroid Eksen? (HPT) üzerinde yoğunlaşmıştır. Bu çalışmaları sayı bakımından ?Somatotropik Eksen?, ?Hipotalamik-Pitüiter-Gonadal Eksen? (HPG ) ile ilgili ve diğer nöroendokrin eksenlerle ilgili araştırmalar izlemiştir. Bu konudaki araştırmaların daha çok affektif bozukluklarda odaklandığı; bunu seyrek olarak anksiyete bozuklukları, şizofrenik bozukluklar, alkolizm, demans ve anoreksiya nervoza gibi hastalıkların izlediği görülmektedir.

Biz bu makalede, affektif bozukluklarda yapılan HPT eksenle ilgili nöroendokrin çalışmalar gözden geçirilmiştir.

Hypothalamo-pituitary-adrenal axis in depressive disorders
Hypothalamo-pituitary-adrenal(HPA) axis and hypothalamo-pituitary-thyroid (HPT) axis have frequently been studied in psychiatric disorders. Hypothalamo-pituitary-gonadal(HPG) axis, somatotropic axis, and other neuroendocrine axis have been relatively few investigated. Neuroendocrine researches have focused on especially affective disorders, anxiety disorder, but schizophrenic disorders ,alcoholism, dementia, and anorexia nervosa infrequently evaluated.

In this article we reviewed hypothalamo-pituitary-thyroid axis findings in depressive disorders.

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