Dergi Ara >>
Yıl:1992; Cilt: 3; Sayı: 1>> Özet
Türk Psikiyatri Dergisi; 1992;3(1):55-57
Alkol Bağımlılannda BBT Bulguları
YE Evlice, E Atilla, N Özpoyraz, M Ünal, BA Levent
Uzun süre ve aşırı miktarlarda alkol kullananların beyninde işlevsel ve yapısal değişikliklerin ortaya çıktığı bilinmekte ve bu bozuklukları saptayabilmek için çeşitli görüntüleme yöntemlerinden yararlanılmaktadır. Bilgisayarlı beyin tomografisi (BBT) ile yapılan incelemeler, alkol bağımlılarında kortikal atrofi ve ventriküler dilatasyonun yaygın olarak bulunduğunu ortaya konmuştur. Çalışmaya DSM-III-R sınıflamasına göre, alkol bağımlılığı tanısıyla Ç. Ü. Tıp Fakültesi Psikiyatri Anabilim Dalında yatırılarak izlenen 30 erkek hasta alındı. Hastaların yaşı 24 ile 58 arasında olup ortalama 40.4 idi. Kontrol grubu olarak yaş grubu eşleştirilmiş, alkol sorunu olmayan 30 sağlıklı erkek alındı. BBT incelemesinde aksiyel planda 10mm aralıklarla kesitler alınarak Evans indeksi, bifrontal indeks, 3. ventrikül indeksi ve sulkus girus indeksi değerleri araştırıldı. Santral atrofi yönünden çalışma ve kontrol grubu arasında bir fark yoktu. Oysa alkol bağımlısı grupta anlamlı düzeyde kortikal atrofi bulundu.

CT Findings in Alcohol Dependent Patients
Consumption of large amounts of alcohol for a long time may cause structural and functional abnormalities in the brain. The examinations by computerized tomography (CT) revealed that cortical atrophy and ventricular dilatation are common in alcohol dependent patients. In this study CT changes have been examined in 30 male alcohol dependent patients (ages ranged 25-58, mean 40.4) as defined by DSM-III-R. Age matched 30 healthy males without drinking problem have been taken as a control group. No significant difference found in the aspects of ventricular dilatation and sulcal widening between the subjects and the controls. On the other hand, significant cortical atrophy has been found in the alcohol dependent patients.

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