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Yıl:2017; Cilt: 20; Sayı: 4>> Özet
TAM METİN
Klinik Psikiyatri Dergisi; 2017;20(4):332-333
Çocuklarda ve Ergenlerde Paliperidonun Metabolik Etkileri: Bir OlguSunumu
Mİ Kefal, H Kandemir, ŞY Sapmaz, M Öztürk, Y Özkan, ÖG Özkan
Manisa Celal Bayar Üniversitesi Tıp Fakültesi, Manisa
Son yıllarda atipik antipsikotiklerin çocuklar ve ergenlerde kullanımı artmıştır. 16 yaşındaki erkek hasta, paliperidonu 3 yıl kullandığını ve bu dönemde kilo aldığını bildirmiştir. Kliniğimizde hastaya tedavi başlanmasıyla çeşitli laboratuvar testleri yapıldı. Test sonucuna göre paliperidonun 3 yıllık kullanımının hastada açlık kan şekeri, total kolesterol, düşük yoğunluklu lipoprotein, trigliserid ve prolaktin düzeylerini önemli ölçüde artırdığı açıktır. İlaç kesildikten sonra hastanın metabolik parametreleri normal aralığa düştü. Bu nedenle, paliperidon, 18 yaşın altındaki hastalar için yan etkilere dayalı olarak dikkatle kullanılmalıdır.
Paliperidone Metabolic Effects in Children and Adolescents: A Case Report
The use of atypical antipsychotics in children and adolescents has increased in recent years. A 16-year-old male patient reported that he had used paliperidone for 3 years and had gained weight during this period. Various laboratory tests were performed when the patient started treatment in our clinic. It is evident from the test result that 3-year use of paliperidone dramatically increased fasting blood sugar, total cholesterol, low-density lipoprotein, triglycerides and prolactin levels in the patient. The metabolic parameters of the patient decreased into the normal range once the medication was stopped. Thus, paliperidone should be used carefully based on the side effects for patients under 18 years of age.

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