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Yıl:1995; Cilt: 6; Sayı: 4>> Özet
Türk Psikiyatri Dergisi; 1995;6(4):277-284
Parkinson Hastalığında Depresyon ve Bilişsel Yeti Yitimi
A AKDEMİR, SD ÖRSEL, E KILIÇ, H KAYIMTU, H ÖZBAY
Depresyon ve demans Parkinson hastalığında sık görülmektedir. Yaklaşık olarak hastaların üçte birinde depresyon görülür. Bu çalışmada Parkinson hastalığında görülen depresyonun, Parkinson semptomları ve bilişsel yetiyitimi ile ilişkileri ele alınmıştır. Bu amaçla İdiyopatik Parkinson hastalığı tanısı alan 66 hasta değerlendirilmiştir. Hastalara depresyon tanısı SCID-P (Structured Clinical Interview for DSM-III-R) ile konulmuştur. Buna göre hastaların %28.8’inde depresif bozukluk (%15.2 major depresyon, %13.6 distimi) saptanırken, %30,3’ünde ciddi bilişsel yeti yitimi saptanmıştır. Depresif bozukluk saptanan grupta erkeklerin oranının fazla olduğu (%78.9) ve daha genç oldukları gözlenmiştir. Parkinson hastalığı bulguları, tutulum yeri ve MRI bulguları ile depresyon varlığı arasında bir ilişki saptanmamıştır.

Depression and Cognitive Impairment in Parkinson’s Disease
Depression and dementia are commonly seen in Parkinson’s disease. Nearly one in three patients have depression. In this research depression in Parkinson’s disease is evaluated in terms of its relationships with Parkinson symptoms and cognitive impairment. 66 patients with Idiopathic Parkinson’s disease were evaluated for this aim. Depressive disorders diagnosed by SCID-P were seen in %28.8 (%15.5 major depression, %13.6 dysthymic disorder) and %30.3 of patients showed serious cognitive impairment. In the depressive group, male/female ratio (%78.2) were higher and they were younger significantly. There was no relationship between Parkinson’s disease symptoms, lateralized motor disturbances, MRI findings and depression.

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