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Yıl:1997; Cilt: 8; Sayı: 3>> Özet
Türk Psikiyatri Dergisi; 1997;8(3):170-176
Psikotik Özellikli Olan ve Olmayan Majör Depresyonun Klinik Özelliklerinin Karşılaştırılması
G AYDO?AN, C KAPTANO?LU, G AKSARAY, A EROL, G SEBER
Bu çalışmada, psikotik özellikli major depresyonun (PD), psikotik özellikleri olmayan major depresyondan (MD) klinik özellikleri açısından farklı bir sendrom olup olmadığının araştırılması amaçlanmıştır. DSM-III-R tanı ölçütlerine göre PD tanısı almış 27 hasta, çalışma kapsamına alınmıştır. Çalışma grubu; sosyodemografik, sosyokültürel özellikler ve depresyonun klinik özellikleri açılarından DSM-III-R tanı ölçütlerine göre MD tanısı almış 21 hasta ile karşılaştırılmıştır. Çalışmamızda, bölümümüzce hazırlanan anket formu, DSM-III R tanıları için Yapılandırılmış Klinik Görüşme Çizelgesi (SCID), Hamilton Depresyon (HAM-D) Ölçeği ve Kısa psikiyatrik Değerlendirme Ölçeği (KPDÖ) veri toplama araçları olarak kullanılmıştır. Psikotik özellikli major depresyon ve MD olan hastaların sosyodemografik ve sosyokültürel özellikleri incelendiğinde önemli bir farklılık bulunmamıştır. Psikotik özellikli major depresyonu olan hastalarda HAM-D Ölçeği toplam puanları MD olan hastalara göre daha yüksek bulunmuştur (p<0.01). Psikotik özellikli major depresyonlu hastalarda depresif mizaç (p<0.05), suçluluk (p<0.01), ajitasyon (p<0.01), psişik anksiyete (p<0.05), depersonalizasyon (p<0.01)ve paranoid belirtilerin (p<0.01) daha şiddetli olduğu bulunmuştur. KPDÖ toplam puanları PD’lu hastalarda MD’lu hastalardan daha yüksek olarak saptanmıştır (p<0.01). Bulgular, PD’nun MD’dan ayrı bir sendrom olmayıp, MD’nun daha şiddetli bir alt grubu olduğu tezini desteklemektedir.

Clinical Comparison of Psychotic Major Depression With Nonpsychotic Major Depression
In this study we investigated whether the psychotic major depression (PD) was a distinct syndrome from the nonpsychotic major depression (MD). 27 patients who were diagnosed as DSM-III-R major depression with psychotic features were compared with 21 patients who were diagnosed as major depression without psychotic features in terms of their sociocultural, demographic and clinical characteristics. All were also evaluated with psychiatric interview form. Structured Clinical Interview for DSM-III-R (SCID), the Hamilton depression Rating Scale (HAM-D) and the Brief Psychiatric Rating Scale (BPRS). There was no difference in terms of sociocultural and demographic features. Total scores of HAM-D of the patients with PD were higher than the patients with MD (p<0.01). Depressed mood subscore (p<0.05), guilt subscore (p<0.01), agitation subscore (p<0.01), psychic anxiety subscore (p<0.05), depersonalization subscore (p<0.01), and paranoid symptoms (p<0.01) at HAM-D and the total scores of BPRS of the patients with PD were higher than the others. Our data support that PD is not a distinct syndrome from major depression but is a severe form of major depression.

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