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Yıl:2017; Cilt: 54; Sayı: 1>> Özet
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Nöropsikiyatri Arşivi; 2017;54(1):72-77
Demir Eksikliği Anemisi Olan Kadın Hastalarda Erişkin Dikkat Eksikliği Hiperaktivite Belirtilerinin ve Tanısının Araştırılması
K Demirci, FY Baş, B Arslan, Z Salman, A Akpınar, A Demirdaş
Süleyman Demirel Üniversitesi, Isparta
Amaç: Demir eksikliği tanısı almış kadınlarda erişkin dikkat eksikliği hiperaktivite bozukluğu (DEHB) tanısının ve belirtilerinin araştırılması, klinik özelliklerle ilişkilerinin incelenmesi ve demir eksikliği olmayan kadınlarla karşılaştırılmasıdır. Yöntem: Yeni tanı konulan 83 demir eksikliği anemili hasta ve 70 sağlıklı kontrol çalışmaya dahil edilmiştir. Tüm katılımcılar sosyodemografik veri formu, eksen I bozukluklar için yapılandırılmış klinik görüşme (SCID-I) ve Wender-Utah Derecelendirme Ölçeği (WUDÖ) ile değerlendirilmiş, WUDÖ puanı 36 ve üzerinde olan bireylere Erişkin DEB/DEHB Tanı ve Değerlendirme Envanteri uygulanarak DSM-5 tanı ölçütlerine dayalı tanısal görüşme yapılmıştır. Bulgular: Çalışmamızda, demir eksikliği anemili hastaların %22,9’unun, sağlıklı kontrollerin %12,9’unun WUDÖ puanlarının 36 ve üzerinde olduğu bulunmuştur. WUDÖ puanı 36 ve üzerinde olan katılımcılar Erişkin DEB/DEHB Tanı ve Değerlendirme Envanteri ve DSM-5 tanı ölçütlerine dayalı tanısal görüşme ile değerlendirildiklerinde demir eksikliği anemisi grubunda 15 hastaya, kontrol grubunda 2 hastaya erişkin DEHB tanısı konulmuştur (p=0,007). Demir eksikliği anemisi grubunda WUDÖ puanları kontrol grubundan anlamlı düzeyde yüksek saptanmıştır (p=0,002). WUDÖ puanlarının, serum demir ve ferritin düzeyleri ile anlamlı negatif ilişkili (sırasıyla, r=-0,166, p<0.05, r=-0,255, p<0.01), serum demir bağlama kapasitesi ile anlamlı pozitif ilişkili olduğu bulunmuştur (r=0,255, p<0.01). Sonuç: Demir eksikliği anemisi olan hastalarda erişkin DEHB’nin yaygınlığı genel popülasyondaki yaygınlığından daha yüksek bulunmuştur. Erişkin DEHB’nin erken tanınması ve tedavisi demir eksikliği anemili hastalarda olumlu katkılar sağlayabilir.
The Investigation of Symptoms and Diagnoses of Adult-Attention Deficit/Hyperactivity Disorder in Women with Iron Deficiency Anemia
Introduction: The aim of this study was to investigate symptoms and diagnoses of Adult-Attention Deficit/Hyperactivity Disorder (ADHD) in women with iron deficiency anemia, to evaluate relationship between ADHD with clinical features and to compare with the women without iron deficiency anemia. Methods: Eighty-three newly diagnosed iron deficiency anemia patients and 70 healthy controls were included in this study. All participants were assessed using a sociodemographic form, Structured Clinical Interview I (SCID-I), Wender Utah Rating Scale (WURS); Moreover, participants having WURS scores 36 and above were also assessed using the Adult ADD/ADHD Evaluation Scale and interviewed according to DSM-5 criteria. Results: In the study, 22.9% of patients with iron deficiency anemia and 12.9% of healthy controls were found to have WURS scores 36 and above. Fifteen patients (18.1%) in iron deficiency anemia group and two patients (2.9%) in control group had adult ADHD, when they were evaluated with Adult ADD/ADHD Evaluation Scale and interviewed according to DSM-5 criteria (p=0.007). The patients with iron deficiency anemia had significantly higher WURS scores compared to controls (p=0.002). The levels of iron and ferritin had negative correlation (r=-0.166, p<0.05, r=-0,255, p<0.01, respectively) and the levels of serum iron binding capacity had positive correlation (r=0.255, p<0.01). Conclusion: The prevalence of adult ADHD is higher than those reported for general population in patients with iron deficiency anemia. Early diagnose and treatment of adult ADHD may positively contribute to the patients with iron deficiency anemia.

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