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Yıl:2017; Cilt: 54; Sayı: 1>> Özet
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Nöropsikiyatri Arşivi; 2017;54(1):11-14
Türkiye’de Orta Karadeniz Bölgesindeki Multıpl Skleroz Prevelansı ve Hastaların Demografik Özellikleri
N Akdemir, M Terzi, N Arslan, M Onar
Ondokuz Mayıs Üniversitesi, Samsun
Amaç: Multipl skleroz (MS), dünya genelinde prevelansı gittikçe artan bir merkezi sinir sistemi demiyelinizan hastalığıdır. Küçük ölçekli çalışmalar dışında, Türkiye'de MS sıklığı ile ilgili verilerde bir eksiklik vardır. Bu çalışmada Orta Karadeniz Bölgesi'nde MS prevalansı ve hastaların demografik özelliklerinin belirlenmesi amaçlanmıştır. Yöntem: Orta Karadeniz bölgesinde yaşayan ve MS tanısı almış hastalar çalışmaya dahil edildi. Çalışma Türkiye'de hastane tabanlı planlandı. Bulgular: 1787 hasta ile görüşüldü ve bunlardan 1584 ‘ünde tanı doğrulandı. Hastalığın ortalama başlangıç yaşı 29,39±7,6 yıl idi. Hastaların 1299’u (%81,9) relapsing remitting MS, 74’ü sekonder progresif MS, 77’si relapsing progresif MS, 47’si primer progresif MS ve 87’si klinik izole sendrom klinik formundaydı. Sonuç: Orta Karadeniz Bölgesi MS prevalansı yüksek riskli bir coğrafi bölge olarak bulunmuştur. Bu çalışma, Türkiye'de MS prevelansı ile ilgili en büyük coğrafi dağılımı kapsayan en kapsamlı epidemiyolojik çalışmadır.
Prevalence of Multiple Sclerosis in the Middle Black Sea Region of Turkey and Demographic Characteristics of Patients
Introduction: Multiple sclerosis (MS), a demyelinating disease of the central nervous system, is increasing in prevalence worldwide. Other than small-scale studies, there is a scarcity of data on the prevalence of MS in Turkey. The present study aimed to elucidate the prevalence of MS in the Middle Black Sea Region and the demographic characteristics of patients. Methods: Patients living in the Middle Black Sea Region and who were diagnosed with MS were included. The study was designed based hospital of Turkey. Results: A total of 1,787 patients were interviewed, and a diagnosis of MS was confirmed in 1,584. The prevalence of MS was found to be 43.2/100,000 in the Middle Black Sea Region; this was calculated based on the total population and number of patients in the provinces and districts in this region. The mean age at the disease onset was 29.39±7.6 years. Among the patients, 1,299 (81.9%) had relapsing-remitting MS, 74 had secondary progressive MS, 77 had relapsing-progressive MS, 47 had primary progressive MS, and 87 had clinically isolated syndrome. Conclusion: The Middle Black Sea Region was found to have a high risk for the prevalence of MS. This study is the most comprehensive epidemiologic study having the largest geographical distribution on the prevalence of MS in Turkey.

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