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Yıl:2016; Cilt: 2; Sayı: 3>> Özet
Türkiye Klinikleri Çocuk Psikiyatrisi Özel Dergisi; 2016;2(3):47-53
Çocuk ve Ergenlerde Anksiyete Bozukluklarında Farmakolojik Tedavi Yaklaşımları
M Öztürk, G Karaçetin
Hasan Kalyoncu Üniversitesi, Gaziantep
Çocuk ve ergenlerde anksiyete bozukluklarının tedavisi planlanırken psikoeğitim, bilişsel davranışçı terapi, aile terapisi ve farmakoterapinin birlikte kullanıldığı bir multimodal tedavi şekli göz önünde bulundurulmalıdır. Bilimsel çalışmalarda tutarlı bir şekilde etkinlik ve güvenilirliklerinin gösterilmesi nedeniyle pediatrik anksiyete bozukluklarının farmakoterapisinde ilk seçenek seçici serotonin gerialım inhibitörleri (SSGİ)'dir. SSGİ'lerin ayrılma kaygısı bozukluğu, yaygın anksiyete bozukluğu, sosyal fobi ve selektif mutizm tedavisinde etkili olduğu gösterilmiştir. Pediatrik anksiyete bozukluklarının farmakoterapisinde ilk seçenek SSGİ olmakla birlikte; serotonin ve noradrenalin gerialım inhibitörleri, trisiklik antidepresanlar ve benzodiazepinler gibi birçok ilaç tedavide kullanılabilmektedir. Anksiyete bozuklukluğu olan bir çocuğun tedavi seçiminde anksiyete bozukluğunun şiddeti ve işlevsellik üzerindeki etkisi, komorbid durumlar, psikososyal faktörler, yaş ve gelişimsel durum değerlendirilmelidir.
Pharmacological Treatment Approaches in Children and Adolescents with Anxiety Disorders
A multimodal treatment approach which combines psychoeducation, cognitive-behavioral therapy, family therapy and pharmacotherapy should be considered in the treatment planning of children and adolescents with anxiety disorders.The selective serotonin reuptake inhibitors (SSRIs) are the first line agents for pediatric anxiety disorders as their efficacy and safety are replicated consistently in scientific studies. The efficacy of SSRIs have been established in the treatment of separation anxiety disorder, generalized anxiety disorder, social phobia and selective mutism. Even though SSRIs are the first line choice in pharmacotherapy, a number of medications can be used in the treatment of pediatric anxiety disorders like serotonin norepinephrine reuptake inhibitors, tricyclic antidepressants and benzodiazepines. Selection of the specific treatment modalities for an individual child should include consideration of the severity and impairment of the anxiety disorder, comorbid disorders, psychosocial factors, age and developmental status.

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