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Yıl:2017; Cilt: 9; Sayı: 3>> Özet
TAM METİN
Psikiyatride Güncel Yaklaşımlar; 2017;9(3):317-328
Sentetik Kannabinoidler
AO İbiloğlu, A Atlı, M Güneş
Dicle Üniversitesi, Diyarbakır
Kanabinoidlerin bir alt grubu olan sentetik kanabinoidlerin uyuşturucu madde olarak kullanımları tüm dünyada oldukça yaygındır. Esrar ve sentetik kanabinoidlerin her ikisinin de aynı reseptörleri (CB1 reseptörleri ve CB2 reseptörleri) uyarmalarına rağmen, yapılan çalışmalar sentetik kanabinoidlerin esrara göre çok daha potent olduğunu göstermiştir. Sentetik kanabinoidlerin uzun süre kullanımı, bilinen birçok yasa dışı madde kullanımına benzer şekilde ölüm ile bile sonuçlanabilen, şiddetli fiziksel ve psikolojik belirtilere neden olabilir. Ana tedavi çoğunlukla belirtilerin yönetilmesi ve destekleyici bakımı içermektedir. Bu makalenin amacı kullanımı giderek artan sentetik kanabinoidlerin klinik ve farmakolojik özelliklerinin tartışılmasıdır.
Synthetic Cannabinoids
Synthetic cannabinoids which is a subgroup of cannabinoids are commonly used for recreational drug use throughout the whole world. Although both marijuana and synthetic cannabinoids stimulate the same receptors, cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2), studies have shown that synthetic cannabinoids are much more potent than marijuana. The longer use of synthetic cannabinoids can cause severe physical and psychological symptoms that might even result in death, similar to many known illicit drugs. Main treatment options mostly involve symptom management and supportive care. The aim of this article is to discuss clinical and pharmacological properties of the increasingly used synthetic cannabinoids.

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