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Yıl:2016; Cilt: 17; Sayı: 2>> Özet
TAM METİN
Bağımlılık Dergisi; 2016;17(2):82-94
Üç Olgu ile Sentetik Kannabinoidler ve Kliniğe Yansımaları: Bir Gözden Geçirme
M Altıntaş, L İnanç, H Güleç
Erenköy Ruh ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi, İstanbul
Sentetik kannabinoidler günümüzde toplum sağlığını ve güvenliğini bozan önemli bir problem haline gelmiştir. Bu maddelerin özellikle gençler arasındaki kullanımı tüm dünyada olduğu gibi son yıllarda ülkemizde de artış göstermiştir. Sentetik esrar türevlerinin birçok isimleri olmakla beraber Türkiye'de "Bonzai" ve "Jamaika" isimleri yaygın olarak kullanılmaktadır. Bu maddelerin oldukça ucuz ve kolay ulaşılabilir olmaları yaygınlaşmasına sebep olmaktadır. Sentetik kannabinoidlerin farmakolojik for-mülasyonu maddeyi tasarlayan kişiler tarafından sürekli değiştirildiği için rutin madde tarama testlerinde saptanamamaktadır. Heterojen yapıları ortaya çıkabilecek klinik tablolar hakkında öngörüde bulunmayı zorlaştırmaktadır. Birçok sistemi etkileyebilen ve hayatı tehdit edebilecek tablolara yol açabilen bu maddelerin klinik görünümleri oldukça değişkendir. Sentetik kanna-binoid kullanımı sonrası kişiler yaşadıkları fiziksel ve psikiyatrik belirtiler nedeniyle sıklıkla acil servislere, psikiyatri polikliniklerine ve aile hekimlerine başvurmaktadır. Bu durum birçok sağlık çalışanı için endişe verici hale gelmiştir. Bu maddelerin neden olduğu klinik tabloları tanıma, müdahale ve tedavi konusunda multidisipliner bir yaklaşım gerekmektedir. Bu yazıda sentetik kannabinoid kullanan üç olgu sunulmuş ve bu maddelerin neden olabileceği farklı klinik durumlarla ilgili dizin gözden geçirilmiştir.
Three Case Reports with Synthetic Cannabinoids and Their Clinical Reflection: A Review
Synthetic cannabinoids (SCs) have become a problem of public health and security nowadays. Their use has increased especially among young people both in the world and in our country. Synthetic marijuana varieties have many names such as Bonsai and Jamaica being the most popular in Turkey. The cheapness and easy accessibility of these drugs cause their widespread popularity. SCs cannot be detected with current screening tests, because their pharmacological formulations are often changed by the drug designers. The heterogeneity of their ingredients makes it difficult to predict the clinical picture. These drugs can affect multiple systems with life threatening consequences presenting varying clinical views. After SC consumption, SC users complain of physiological and psychiatric symptoms resulting in applying to emergency rooms, psychiatric clinics and family physicians. This situation has become worrisome for many health practitioners. There is a need for a multidisciplinary approach for recognition, intervention and treatment of the clinical manifestation resulting from SC use. We present three cases of SC use and review the literature on the resulting different clinical manifestation of SC use.

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